Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N= 53 949)

G Davies, N Armstrong, JC Bis, J Bressler… - Molecular …, 2015 - nature.com
General cognitive function is substantially heritable across the human life course from
adolescence to old age. We investigated the genetic contribution to variation in this …

Genetic influences on cognitive function using the Cambridge Neuropsychological Test Automated Battery

JJ Singer, AJ MacGregor, LF Cherkas, TD Spector - Intelligence, 2006 - Elsevier
The genetic relationship between intelligence and components of cognition remains
controversial. Conflicting results may be a function of the limited number of methods used in …

DNA markers associated with general and specific cognitive abilities

SA Petrill, R Plomin, GE McClearn, DL Smith, S Vignetti… - Intelligence, 1996 - Elsevier
Multivariate quantitative genetic research suggests a hierarchical model of cognitive abilities
where genetic effects are largely general, cutting across most cognitive abilities. Some …

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N= 280,360)

G Davies, M Lam, SE Harris, JW Trampush, M Luciano… - BioRxiv, 2017 - biorxiv.org
General cognitive function is a prominent human trait associated with many important life
outcomes,, including longevity. The substantial heritability of general cognitive function is …

The promise and pitfalls of molecular genetics

P Aldhous - Science, 1992 - science.org
individual genes affecting intelligence. The risk inherent in such studies, however, is that
spurious associations may be picked up. The most obvious source of error is stratification …

Most reported genetic associations with general intelligence are probably false positives

CF Chabris, BM Hebert, DJ Benjamin… - Psychological …, 2012 - journals.sagepub.com
General intelligence (g) and virtually all other behavioral traits are heritable. Associations
between g and specific single-nucleotide polymorphisms (SNPs) in several candidate genes …

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB

AC Need, DK Attix, JM McEvoy, ET Cirulli… - Human molecular …, 2009 - academic.oup.com
Psychiatric disorders such as schizophrenia are commonly accompanied by cognitive
impairments that are treatment resistant and crucial to functional outcome. There has been …

Genetics and the brain: many pathways to enlightenment

MC O'Donovan, MJ Owen - Human Genetics, 2009 - Springer
This special review issue on Neurological and Psychiatric Diseases and Traits focuses upon
a number of phenotypes which, while very different, result from impairment of, or variation in …

Logical and methodological issues affecting genetic studies of humans reported in top neuroscience journals

CR Grabitz, KS Button, MR Munafò… - Journal of Cognitive …, 2018 - direct.mit.edu
Genetics and neuroscience are two areas of science that pose particular methodological
problems because they involve detecting weak signals (ie, small effects) in noisy data. In …

Uncovering the genetic underpinnings of cognition

TW Robbins, S Kousta - Trends in Cognitive Sciences, 2011 - cell.com
No one today can ignore the genetic approach to cognition and behavior, given the huge
achievements of the Human Genome Project (http://www. ornl. gov/sci/techresources …