Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N= 53 949)
General cognitive function is substantially heritable across the human life course from
adolescence to old age. We investigated the genetic contribution to variation in this …
adolescence to old age. We investigated the genetic contribution to variation in this …
Genetic influences on cognitive function using the Cambridge Neuropsychological Test Automated Battery
JJ Singer, AJ MacGregor, LF Cherkas, TD Spector - Intelligence, 2006 - Elsevier
The genetic relationship between intelligence and components of cognition remains
controversial. Conflicting results may be a function of the limited number of methods used in …
controversial. Conflicting results may be a function of the limited number of methods used in …
DNA markers associated with general and specific cognitive abilities
SA Petrill, R Plomin, GE McClearn, DL Smith, S Vignetti… - Intelligence, 1996 - Elsevier
Multivariate quantitative genetic research suggests a hierarchical model of cognitive abilities
where genetic effects are largely general, cutting across most cognitive abilities. Some …
where genetic effects are largely general, cutting across most cognitive abilities. Some …
Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N= 280,360)
General cognitive function is a prominent human trait associated with many important life
outcomes,, including longevity. The substantial heritability of general cognitive function is …
outcomes,, including longevity. The substantial heritability of general cognitive function is …
The promise and pitfalls of molecular genetics
P Aldhous - Science, 1992 - science.org
individual genes affecting intelligence. The risk inherent in such studies, however, is that
spurious associations may be picked up. The most obvious source of error is stratification …
spurious associations may be picked up. The most obvious source of error is stratification …
Most reported genetic associations with general intelligence are probably false positives
General intelligence (g) and virtually all other behavioral traits are heritable. Associations
between g and specific single-nucleotide polymorphisms (SNPs) in several candidate genes …
between g and specific single-nucleotide polymorphisms (SNPs) in several candidate genes …
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB
AC Need, DK Attix, JM McEvoy, ET Cirulli… - Human molecular …, 2009 - academic.oup.com
Psychiatric disorders such as schizophrenia are commonly accompanied by cognitive
impairments that are treatment resistant and crucial to functional outcome. There has been …
impairments that are treatment resistant and crucial to functional outcome. There has been …
Genetics and the brain: many pathways to enlightenment
MC O'Donovan, MJ Owen - Human Genetics, 2009 - Springer
This special review issue on Neurological and Psychiatric Diseases and Traits focuses upon
a number of phenotypes which, while very different, result from impairment of, or variation in …
a number of phenotypes which, while very different, result from impairment of, or variation in …
Logical and methodological issues affecting genetic studies of humans reported in top neuroscience journals
CR Grabitz, KS Button, MR Munafò… - Journal of Cognitive …, 2018 - direct.mit.edu
Genetics and neuroscience are two areas of science that pose particular methodological
problems because they involve detecting weak signals (ie, small effects) in noisy data. In …
problems because they involve detecting weak signals (ie, small effects) in noisy data. In …
Uncovering the genetic underpinnings of cognition
TW Robbins, S Kousta - Trends in Cognitive Sciences, 2011 - cell.com
No one today can ignore the genetic approach to cognition and behavior, given the huge
achievements of the Human Genome Project (http://www. ornl. gov/sci/techresources …
achievements of the Human Genome Project (http://www. ornl. gov/sci/techresources …