The pressure towards innovation and creation of new model systems in regenerative
medicine and cancer research has fostered the development of novel potential therapeutic …

The kidney function of patients with chronic kidney disease (CKD) is impaired irreversibly.
Organ transplantation is the only treatment to restore kidney function in CKD patients. The …

The kidney is a vital organ that regulates the bodily fluid and electrolyte homeostasis via
tailored urinary excretion. Kidney injuries that cause severe or progressive chronic kidney …

Technical advances in the development of organoid systems enable cell lines, primary adult
cells, or stem or progenitor cells to develop into diverse, multicellular entities, which can self …

Kidney organoids derived from human induced pluripotent stem cells bear the potential to
be used as a regenerative medicine renal replacement therapy. Advances in developmental …

The kidney is one of the most complex organs composed of multiple cell types, functioning to
maintain homeostasis by means of the filtering of metabolic wastes, balancing of blood …

A kidney organoid is a three-dimensional (3D) cellular aggregate grown from stem cells in
vitro that undergoes self-organization, recapitulating aspects of normal renal development to …

The kidney is a highly complex organ in the human body. Although creating an in vitro
model of the human kidney is challenging, tremendous advances have been made in recent …

Kidney organoids derived from human pluripotent stem cells constitute a novel model of
disease, development, and regenerative therapy. Organoids are human, experimentally …

Kidney organoids have potential uses in disease modelling, drug screening and
regenerative medicine. However, novel cost-effective techniques are needed to enable …