Long-term effect on in vitro cloning efficiency after treatment of somatic cells with Xenopus egg extract in the pig
In somatic cell nuclear transfer (SCNT), donor cell reprogramming is considered as a
biologically important and vulnerable event. Various donor cell pre-treatments with Xenopus …
biologically important and vulnerable event. Various donor cell pre-treatments with Xenopus …
Improved in vitro development of cloned bovine embryos using S‐adenosylhomocysteine, a non‐toxic epigenetic modifying reagent
S Jafari, MS Hosseini, M Hajian… - Molecular …, 2011 - Wiley Online Library
In this study, fibroblast cells were stably transfected with mouse POU5F1 promoter‐driven
enhanced green fluorescent protein (EGFP) to investigate the effect of S …
enhanced green fluorescent protein (EGFP) to investigate the effect of S …
[HTML][HTML] Inhibition of aberrant DNA re-methylation improves post-implantation development of somatic cell nuclear transfer embryos
Somatic cell nuclear transfer (SCNT) enables cloning of differentiated cells by
reprogramming their nuclei to a totipotent state. However, successful full-term development …
reprogramming their nuclei to a totipotent state. However, successful full-term development …
[HTML][HTML] DNA methylation patterns in tissues from mid-gestation bovine foetuses produced by somatic cell nuclear transfer show subtle abnormalities in nuclear …
C Couldrey, RSF Lee - BMC developmental biology, 2010 - Springer
Background Cloning of cattle by somatic cell nuclear transfer (SCNT) is associated with a
high incidence of pregnancy failure characterized by abnormal placental and foetal …
high incidence of pregnancy failure characterized by abnormal placental and foetal …
[HTML][HTML] Genome-wide dynamic profiling of histone methylation during nuclear transfer-mediated porcine somatic cell reprogramming
Z Cao, Y Li, Z Chen, H Wang, M Zhang, N Zhou, R Wu… - PloS one, 2015 - journals.plos.org
The low full-term developmental efficiency of porcine somatic cell nuclear transfer (SCNT)
embryos is mainly attributed to imperfect epigenetic reprogramming in the early embryos …
embryos is mainly attributed to imperfect epigenetic reprogramming in the early embryos …
Epigenetic reprogramming, gene expression and in vitro development of porcine SCNT embryos are significantly improved by a histone deacetylase inhibitor—m …
Y Song, T Hai, Y Wang, R Guo, W Li, L Wang… - Protein & …, 2014 - academic.oup.com
Insufficient epigenetic reprogramming of donor nuclei is believed to be one of the most
important causes of low development efficiency of mammalian somatic cell nuclear transfer …
important causes of low development efficiency of mammalian somatic cell nuclear transfer …
[PDF][PDF] Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos
J Cho, S Kang, BC Lee - Journal of Veterinary Science, 2014 - synapse.koreamed.org
This study was conducted to investigate the expression of three genes related to early
embryonic development in bovine transgenic cloned embryos. To accomplish this …
embryonic development in bovine transgenic cloned embryos. To accomplish this …
Normal DNA methylation status in sperm from a somatic cell cloned bull and their fertilized embryos
KI Yamanaka, K Yamashita, H Khatun… - Animal Science …, 2018 - Wiley Online Library
Epigenetic reprogramming confers totipotency even during somatic cell nuclear transfer
(SCNT), which has been used to clone various animal species. However, as even …
(SCNT), which has been used to clone various animal species. However, as even …
[HTML][HTML] Simultaneous inhibition of histone deacetylases and RNA synthesis enables totipotency reprogramming in pig SCNT embryos
Combining somatic cell nuclear transfer (SCNT) with genome editing technologies has
emerged as a powerful platform for the creation of unique swine lineages for agricultural and …
emerged as a powerful platform for the creation of unique swine lineages for agricultural and …
Analysis of apoptosis and methyltransferase mRNA expression in porcine cloned embryos cultured in vitro
S Ju, R Rui, Q Lu, P Lin, H Guo - Journal of assisted reproduction and …, 2010 - Springer
Purpose The purpose of this study was to investigate the relationship of porcine somatic cell
nuclear transfer (SCNT) embryo developmental competence with embryonic cell apoptosis …
nuclear transfer (SCNT) embryo developmental competence with embryonic cell apoptosis …