Objectives The objective of this work was to synthesize 15 new 1-(5-cyclobutyl-1, 3-oxazol-2-
yl)-3-(sub) phenyl/pyridylthiourea compounds and evaluate their in vitro and in vivo …

Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term
persistence under conditions of low oxygen tension. A series of thiazolyl-pyrazole …

A series of novel morpholine, thiomorpholine and N-substituted piperazine coupled 2-
(thiophen-2-yl) dihydroquinolines 7a–p was designed and synthesized from 2-acetyl …

In this paper, five novel 5, 5-diphenylpyrrolidine N-aroylthiourea derivatives were
synthesized by stereoselective cycloaddition of N-diphenylmethylene-protected glycine …

In continuation of our research program for new antituberculosis drugs, we have designed,
synthesized and evaluated antimycobacterial activity of new series of 1-[3-(4-benzotriazol …

In the present study, a series of N-{4-[(4-amino-5-sulfanyl-4H-1, 2, 4-triazol-3-yl) methyl]-1, 3-
thiazol-2-yl}-2-substituted-amide (1a–d) derivatives were synthesized in good yields and …

Herein, we report the discovery and structure–activity relationships of 5-substituted-2-[(3, 5-
dinitrobenzyl) sulfanyl]-1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles as a new class of …

Sixteen novel 3-nitro-2-(sub)-5, 12-dihydro-5-oxobenzothiazolo [3, 2-a]-1, 8-naphthyridine-6-
carboxylic acids were synthesized from 2, 6-dimethoxynicotinic acid and 2-aminothiophenol …

Herein described the design, synthesis and antitubercular evaluation of novel series of
dibenzofuran, dibenzothiophene and N-methyl carbazole tethered 2-aminothiazoles and …

Various 2-(sub)-3-fluoro/nitro-5, 12-dihydro-5-oxobenzothiazolo [3, 2-a] quinoline-6-
carboxylic acid derivatives were synthesized from 2-aminothiophenol by a five-step reaction …