The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially
used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis …

Chronic skin wounds represent one of the most common and disabling complications of
diabetes. Endothelial progenitor cells (EPCs) are precursors of endothelial cells and can …

Aims Wound healing is deeply dependent on neovascularization to restore blood flow. The
neovascularization of endothelial progenitor cells (EPCs) through paracrine secretion has …

Background Enhanced angiogenesis can promote diabetic wound healing. Mesenchymal
stem cells (MSCs)-derived exosomes, which are cell-free therapeutics, are promising …

Objectives Skin serves as the major interface between the external environment and body
which is liable to many kinds of injuries. Mesenchymal stem cell (MSC) therapy has been …

Wound healing is a complicated process that contains a number of overlapping and
consecutive phases, disruption in each of which can cause chronic nonhealing wounds. In …

Diabetic wounds remain a great challenge for clinicians due to the multiple bacterial
infections and oxidative damage. Exosomes, as an appealing nanodrug delivery system …

Some scholars have suggested that the clinical application of exosomes derived from
human umbilical cord mesenchymal stem cells (hucMSCs-exo) might represent a novel …

Purpose Chronic refractory wounds are a multifactorial comorbidity of diabetes mellitus with
the characteristic of impaired vascular networks. Currently, there is a lack of effective …

Background Mesenchymal stem cell (MSC)-derived exosomes emerge as promising
candidates for treating delayed wound healing in diabetes due to the promotion of …