[HTML][HTML] Brain tissue iron neurophysiology and its relationship with the cognitive effects of dopaminergic modulation in children with and without ADHD

AD Cascone, F Calabro, W Foran, B Larsen… - Developmental …, 2023 - Elsevier
Children with attention-deficit/hyperactivity disorder (ADHD) exhibit impairments in response
inhibition. These impairments are ameliorated by modulating dopamine (DA) via the …

Reduced basal ganglia tissue-iron concentration in school-age children with attention-deficit/hyperactivity disorder is localized to limbic circuitry

R Shvarzman, D Crocetti, KS Rosch, X Li… - Experimental brain …, 2022 - Springer
Dopamine-related abnormalities in the basal ganglia have been implicated in attention-
deficit/hyperactivity disorder (ADHD). Iron plays a critical role in supporting dopaminergic …

[HTML][HTML] Brain iron levels in attention-deficit/hyperactivity disorder normalize as a function of psychostimulant treatment duration

V Adisetiyo, KM Gray, JH Jensen, JA Helpern - NeuroImage: Clinical, 2019 - Elsevier
Brain iron homeostasis is a dopamine-related mechanism that may be modified with long-
term psychostimulant treatment in attention-deficit/hyperactivity disorder (ADHD). We …

Brain iron concentration in childhood ADHD: A systematic review of neuroimaging studies

HAE Morandini, PA Watson, P Barbaro… - Journal of Psychiatric …, 2024 - Elsevier
Iron deficiency may play a role in the pathophysiology of Attention Deficit/Hyperactivity
Disorder (ADHD). Due to its preponderant function in monoamine catecholamine and myelin …

Neuroimaging human dopamine-related neurophysiology across development

A Parr, B Larsen, F Calabro, B Tervo-Clemmens… - … System Function and …, 2022 - Springer
Measures of dopamine (DA) in vivo in humans have been obtained using positron emission
tomography (PET), however, its invasive nature and exposure to radioactivity has limited its …

[HTML][HTML] Early iron deficiency has brain and behavior effects consistent with dopaminergic dysfunction1–3

B Lozoff - The Journal of nutrition, 2011 - Elsevier
To honor the late John Beard's many contributions regarding iron and dopamine biology,
this review focuses on recent human studies that test specific hypotheses about effects of …

Multimodal MR imaging of brain iron in attention deficit hyperactivity disorder: a noninvasive biomarker that responds to psychostimulant treatment?

V Adisetiyo, JH Jensen, A Tabesh, RL Deardorff… - Radiology, 2014 - pubs.rsna.org
Purpose To comprehensively assess brain iron levels in typically developing control
subjects and patients with attention deficit hyperactivity disorder (ADHD) when …

Iron status in toddlerhood predicts sensitivity to psychostimulants in children

CA Turner, D Xie, BM Zimmerman… - Journal of attention …, 2012 - journals.sagepub.com
Objective: Iron deficiency is associated with impaired dopaminergic signaling and
externalizing behavior. The authors examine, whether iron stores in toddlerhood influence …

Neurobehavioral analysis of developmental iron deficiency in rats

JL Beard, KM Erikson, BC Jones - Behavioural brain research, 2002 - Elsevier
Iron deficiency (ID) in early life alters the course of behavioral and cognitive development in
humans, causing decreased physical activity and responsiveness to the environment. The …

Effects of iron supplementation on attention deficit hyperactivity disorder in children

E Konofal, M Lecendreux, J Deron, M Marchand… - Pediatric …, 2008 - Elsevier
Iron deficiency has been suggested as a possible contributing cause of attention deficit
hyperactivity disorder (ADHD) in children. This present study examined the effects of iron …