Quantitative G6PD deficiency screening in routine malaria diagnostic units in the Brazilian Amazon (SAFEPRIM): an operational mixed-methods study

JD Brito-Sousa, F Murta, S Vitor-Silva, V Sampaio… - Pathogens, 2022 - mdpi.com
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency testing is not
routinely performed before primaquine treatment in most Plasmodium vivax endemic areas …

Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand

P Phompradit, J Kuesap, W Chaijaroenkul… - Malaria journal, 2011 - Springer
Background G6PD deficiency is common in malaria endemic regions and is estimated to
affect more than 400 million people worldwide. Treatment of malaria patients with the anti …

Prevalence and hematological indicators of G6PD deficiency in malaria-infected patients

M Kotepui, K Uthaisar, B PhunPhuech… - Infectious diseases of …, 2016 - Springer
Background This study aimed to evaluate the prevalence and alteration of hematological
parameters in malaria patients with a glucose-6-phosphate dehydrogenase (G6PD) …

Frequency of G6PD Mediterranean in individuals with and without malaria in Southern Pakistan

B Moiz, HM Arshad, A Raheem, H Hayat… - Malaria journal, 2017 - Springer
Background Pakistan has an estimated annual burden of 1.5 million malaria cases. The
current situation calls for an effective malaria control and eradication programme in this …

Single low dose primaquine (0.25 mg/kg) does not cause clinically significant haemolysis in G6PD deficient subjects

G Bancone, N Chowwiwat, R Somsakchaicharoen… - PloS one, 2016 - journals.plos.org
Background Primaquine is the only drug consistently effective against mature gametocytes
of Plasmodium falciparum. The transmission blocking dose of primaquine previously …

Heterogeneity of G6PD deficiency prevalence in Mozambique: a school-based cross-sectional survey in three different regions

B Galatas, L Mabote, W Simone, G Matambisso… - Malaria journal, 2017 - Springer
Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-
linked hereditary enzymatic abnormality that affects more than 400 million people …

Prevalence of G6PD deficiency and submicroscopic malaria parasites carriage in malaria hotspot area in Northwest, Tanzania

A Manjurano, E Lyimo, C Kishamawe, J Omolo… - Malaria Journal, 2023 - Springer
Background The use of primaquine for mass drug administration (MDA) is being considered
as a key strategy for malaria elimination. In addition to being the only drug active against the …

Genotypes and phenotypes of G6PD deficiency among Indonesian females across diagnostic thresholds of G6PD activity guiding safe primaquine therapy of latent …

AW Satyagraha, A Sadhewa, LV Panggalo… - PLoS neglected …, 2021 - journals.plos.org
Background Plasmodium vivax occurs as a latent infection of liver and a patent infection of
red blood cells. Radical cure requires both blood schizontocidal and hypnozoitocidal …

Addressing the gender-knowledge gap in glucose-6-phosphate dehydrogenase deficiency: challenges and opportunities

GJ Domingo, N Advani, AW Satyagraha… - International …, 2019 - academic.oup.com
Abstract Glucose-6-phosphate dehyrdgoenase (G6PD) deficiency is a common X-linked
genetic trait, with an associated enzyme phenotype, whereby males are either G6PD …

Glucose-6-phosphate dehydrogenase (G6PD) deficiency in Ethiopia: absence of common African and Mediterranean allelic variants in a nationwide study

A Assefa, A Ali, W Deressa, W Tsegaye, G Abebe… - Malaria journal, 2018 - Springer
Background Building on the declining trend of malaria in Ethiopia, the Federal Ministry of
Health aims to eliminate malaria by 2030. As Plasmodium falciparum and Plasmodium vivax …