Structure and dynamics of major histocompatibility class Ib molecule H2-M3 complexed with mitochondrial-derived peptides
A Strand, ST Shen, DR Tomchick, J Wang… - Journal of …, 2022 - Taylor & Francis
Presentation of antigenic peptides to T-cell receptors is an essential step in the adaptive
immune response. In the mouse the class Ib major histocompatibility complex molecule, H2 …
immune response. In the mouse the class Ib major histocompatibility complex molecule, H2 …
[HTML][HTML] The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and …
Major histocompatibility complex (MHC) class I molecules (proteins) bind peptides of eight to
ten amino acids to present them at the cell surface to cytotoxic T cells. The class I binding …
ten amino acids to present them at the cell surface to cytotoxic T cells. The class I binding …
[HTML][HTML] Conformational flexibility of the MHC class I α1-α2 domain in peptide bound and free states: a molecular dynamics simulation study
M Zacharias, S Springer - Biophysical journal, 2004 - cell.com
Major histocompatibility complex class I proteins play a key role in the recognition and
presentation of peptide antigens to the host immune system. The structure of various major …
presentation of peptide antigens to the host immune system. The structure of various major …
H2-M3, A FULL-SERVICE CLASS Ib HISTOCOMPATIBILITY ANTIGEN
K Fischer Lindahl, DE Byers, VM Dabhi… - Annual review of …, 1997 - annualreviews.org
▪ Abstract H2-M3 is an MHC class Ib molecule of the mouse with a unique preference for N-
formylated peptides, which may come from the N-termini of endogenous, mitochondrial …
formylated peptides, which may come from the N-termini of endogenous, mitochondrial …
Modeling the interactions of a peptide-major histocompatibility class I ligand with its receptors. I. Recognition by two αβ T cell receptors
D Rognan, A Stryhn, L Fugger, S Lyngbæk… - Journal of computer …, 2000 - Springer
A three-dimensional model of the complex between an Influenza Hemagglutinin peptide, Ha
255− 262, and its restricting element, the mouse major histocompatibility complex (MHC) …
255− 262, and its restricting element, the mouse major histocompatibility complex (MHC) …
Two-dimensional nuclear magnetic resonance analysis of a labeled peptide bound to a class II major histocompatibility complex molecule
PC Driscoll, JD Altman, JJ Boniface… - Journal of molecular …, 1993 - Elsevier
The formation of peptide/major histocompatibility complex (MHC) complexes and their
subsequent recognition by T cells is a pivotal event in the initiation of an immune response …
subsequent recognition by T cells is a pivotal event in the initiation of an immune response …
[HTML][HTML] Molecular dynamics simulations to provide insights into epitopes coupled to the soluble and membrane-bound MHC-II complexes
M Bello, J Correa-Basurto - PLoS One, 2013 - journals.plos.org
Epitope recognition by major histocompatibility complex II (MHC-II) is essential for the
activation of immunological responses to infectious diseases. Several studies have …
activation of immunological responses to infectious diseases. Several studies have …
How T cell receptors interact with peptide‐MHCs: A multiple steered molecular dynamics study
MA Cuendet, V Zoete… - … : Structure, Function, and …, 2011 - Wiley Online Library
The T‐cell receptor (TCR) interaction with antigenic peptides (p) presented by the major
histocompatibility complex (MHC) molecule is a key determinant of immune response. In …
histocompatibility complex (MHC) molecule is a key determinant of immune response. In …
[引用][C] Crystal structure of the MHC class Ib molecule H2-M3
CR Wang, KF Lindahl, J Deisenhofer - Research in immunology, 1996 - Elsevier
M3 is a class Ib protein encoded at the telomeric end of the mouse MHC (Richards et al.,
1989); it is expressed in most tissues in all strains of mice (Fischer Lindahl et al., 1991). M3 …
1989); it is expressed in most tissues in all strains of mice (Fischer Lindahl et al., 1991). M3 …
Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes
D Rognan, L Scapozza, G Folkers, A Daser - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received June 13, 1994® abstract: The class I major histocompatibility
complex-encoded HLA-B* 2705 protein was simulated in complex with six different peptides …
complex-encoded HLA-B* 2705 protein was simulated in complex with six different peptides …