Identification of lung innervating sensory neurons and their target specificity
Known as the gas exchange organ, the lung is also critical for responding to the aerosol
environment in part through interaction with the nervous system. The diversity and specificity …
environment in part through interaction with the nervous system. The diversity and specificity …
Sensory nerves in lung and airways
LY Lee, J Yu - Comprehensive Physiology, 2011 - Wiley Online Library
Sensory nerves innervating the lung and airways play an important role in regulating various
cardiopulmonary functions and maintaining homeostasis under both healthy and disease …
cardiopulmonary functions and maintaining homeostasis under both healthy and disease …
Transcriptional profiling of individual airway projecting vagal sensory neurons
Bronchopulmonary sensory neurons are derived from the vagal sensory ganglia and are
essential for monitoring the physical and chemical environment of the airways and lungs …
essential for monitoring the physical and chemical environment of the airways and lungs …
Mapping of the sensory innervation of the mouse lung by specific vagal and dorsal root ganglion neuronal subsets
The airways are densely innervated by sensory afferent nerves, whose activation regulates
respiration and triggers defensive reflexes (eg, cough, bronchospasm). Airway innervation is …
respiration and triggers defensive reflexes (eg, cough, bronchospasm). Airway innervation is …
Vagal afferent innervation of the airways in health and disease
SB Mazzone, BJ Undem - Physiological reviews, 2016 - journals.physiology.org
Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …
Subsets of afferents are defined by their embryological origin, molecular profile …
Sensory receptors in the airways: neurochemical coding of smooth muscle-associated airway receptors and pulmonary neuroepithelial body innervation
I Brouns, I De Proost, I Pintelon, JP Timmermans… - Autonomic …, 2006 - Elsevier
Mainly due to the lack of conclusive morphological data, correlation between functionally
and morphologically defined lung receptors has so far been unsatisfactory. In the present …
and morphologically defined lung receptors has so far been unsatisfactory. In the present …
Identification of neurotransmitters and co-localization of transmitters in brainstem respiratory neurons
RL Stornetta - Respiratory physiology & neurobiology, 2008 - Elsevier
Identifying the major ionotropic neurotransmitter in a respiratory neuron is of critical
importance in determining how the neuron fits into the respiratory system, whether in …
importance in determining how the neuron fits into the respiratory system, whether in …
Recent advances and contraversies on the role of pulmonary neuroepithelial bodies as airway sensors
Pulmonary neuroepithelial bodies are polymodal sensors widely distributed within the
airway mucosa of mammals and other species. Neuroepithelial body cells store and most …
airway mucosa of mammals and other species. Neuroepithelial body cells store and most …
Evidence for a role of neuroepithelial bodies as complex airway sensors: comparison with smooth muscle-associated airway receptors
D Adriaensen, I Brouns, I Pintelon… - Journal of Applied …, 2006 - journals.physiology.org
The epithelium of intrapulmonary airways in many species harbors diffusely spread
innervated groups of neuroendocrine cells, called neuroepithelial bodies (NEBs). Data on …
innervated groups of neuroendocrine cells, called neuroepithelial bodies (NEBs). Data on …
[HTML][HTML] Vagal sensory neuron subtypes that differentially control breathing
Breathing is essential for survival and under precise neural control. The vagus nerve is a
major conduit between lung and brain required for normal respiration. Here, we identify two …
major conduit between lung and brain required for normal respiration. Here, we identify two …