Antimicrobial Hypochlorous Wound Irrigation Solutions Demonstrate Lower Anti-biofilm Efficacy Against Bacterial Biofilm in a Complex in-vitro Human Plasma Biofilm …

JD Rembe, L Huelsboemer, I Plattfaut… - Frontiers in …, 2020 - frontiersin.org
Biofilms pose a relevant factor for wound healing impairment in chronic wounds. With 78%
of all chronic wounds being affected by biofilms, research in this area is of high priority …

Antibiofilm efficacy of polihexanide, octenidine and sodium hypochlorite/hypochlorous acid based wound irrigation solutions against Staphylococcus aureus …

AM Salisbury, M Mullin, R Chen, SL Percival - Advances in Microbiology …, 2021 - Springer
Infection and the formation of biofilms have been shown to have a significant role in
increased inflammation and delayed wound healing. Wound irrigation solutions are used to …

Comparison of antibiofilm activity of low-concentrated hypochlorites vs polyhexanide-containing antiseptic

J Paleczny, AF Junka, P Krzyżek… - Frontiers in cellular …, 2023 - frontiersin.org
Chronic wound infection is highly associated with morbidity and endangers the patient's life.
Therefore, wound care products must have a potent antimicrobial and biofilm-eradicating …

Treating chronic wounds with hypochlorous acid disrupts biofilm

MC Robson - Today's wound Clinic, 2014 - farmaso.com
Methods: This study evaluates the efficacy of hypochlorous acid as an agent to disrupt
Staphylococcus aureus biofilm in a recognized biofilm model. Staphylococcus aureus …

Comparative analysis of biofilm models to determine the efficacy of antimicrobials

EK Stuermer, M Besser, F Brill, M Geffken… - International Journal of …, 2021 - Elsevier
Biofilms are one of the greatest challenges in today's treatment of chronic wounds. While
antimicrobials kill platonic bacteria within seconds, they are rarely able to harm biofilms. In …

Disruption of biofilms and neutralization of bacteria using hypochlorous acid solution: an in vivo and in vitro evaluation

A Day, A Alkhalil, BC Carney, HN Hoffman… - Advances in skin & …, 2017 - journals.lww.com
OBJECTIVES: The aims of this study were to assess the effectiveness of a hypochlorous
acid–based wound cleanser (Vashe Wound Solution [VWS], SteadMed Medical, Fort Worth …

Effectiveness of a polyhexamethylene biguanide-containing wound cleansing solution using experimental biofilm models

M Rippon, AA Rogers, S Westgate… - Journal of wound …, 2023 - magonlinelibrary.com
Objective: Antiseptics are widely used in wound management to prevent or treat wound
infections, and have been shown to have antibiofilm efficacy. The objective of this study was …

Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model

JL Brown, E Townsend, RD Short, C Williams… - npj Biofilms and …, 2022 - nature.com
Wounds can commonly become infected with polymicrobial biofilms containing bacterial and
fungal microorganisms. Microbial colonization of the wound can interfere with sufficient …

[HTML][HTML] Plasma activated water as a pre-treatment strategy in the context of biofilm-infected chronic wounds

HKN Vyas, B Xia, D Alam, NP Gracie, JG Rothwell… - Biofilm, 2023 - Elsevier
Healing and treatment of chronic wounds are often complicated due to biofilm formation by
pathogens. Here, the efficacy of plasma activated water (PAW) as a pre-treatment strategy …

In vitro Activity of Antimicrobial Wound Dressings on P. aeruginosa Wound Biofilm

EK Stuermer, I Plattfaut, M Dietrich, F Brill… - Frontiers in …, 2021 - frontiersin.org
The treatment of acute and chronic infected wounds with residing biofilm still poses a major
challenge in medical care. Interactions of antimicrobial dressings with bacterial load, biofilm …