Polyunsaturated fatty acid intakes and α-linolenic acid metabolism

GC Burdge - The American journal of clinical nutrition, 2011 - ajcn.nutrition.org
1. Chrysohoou C, Panagiotakos DB, Aggelopoulos P, et al. The Mediterranean diet
contributes to the preservation of left ventricular systolic function and to the long-term …

Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients

GK Paschos, F Magkos, DB Panagiotakos… - European journal of …, 2007 - nature.com
Objective: Alpha-linolenic acid (ALA) is the natural precursor of the cardioprotective long-
chain n− 3 fatty acids. Available data indicate a possible beneficial effect of ALA on …

Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study

Y Kawakami, H Yamanaka-Okumura, Y Naniwa-Kuroki… - Nutrition journal, 2015 - Springer
Background The effects of alpha-linolenic acid (ALA) on cardiovascular risk factors
considerably vary between published reports. Therefore, we investigated the effects of 12 …

[HTML][HTML] Circulating concentrations of essential fatty acids, linoleic and α-Linolenic acid, in US adults in 2003–2004 and 2011–2012 and the relation with risk factors for …

KS Petersen, VK Sullivan, VL Fulgoni III, F Eren… - Current Developments …, 2020 - Elsevier
Background The increased use of high-oleic oils to replace trans fat has led to concern
about declining intake of PUFA and the potential for essential fatty acid insufficiency or even …

Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo …

CE Childs, S Kew, YE Finnegan, AM Minihane… - Nutrition journal, 2014 - Springer
Background There is a metabolic pathway by which mammals can convert the omega-3 (n-
3) essential fatty acid α-linolenic acid (ALA) into longer-chain n-3 polyunsaturated fatty acids …

Effect of dietary alpha-linolenic acid on blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials

H Su, R Liu, M Chang, J Huang, Q Jin… - European journal of …, 2018 - Springer
Purpose The aim of the current meta-analysis was to investigate the effect of increasing
dietary ALA intake on the blood concentration of inflammatory markers including tumor …

Dietary α-linolenic acid intake and risk of sudden cardiac death and coronary heart disease

CM Albert, K Oh, W Whang, JAE Manson, CU Chae… - Circulation, 2005 - Am Heart Assoc
Background—α-Linolenic acid, an intermediate-chain n-3 fatty acid found primarily in plants,
may decrease the risk of fatal coronary heart disease (CHD) through a reduction in fatal …

[HTML][HTML] Plant-and marine-derived n− 3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the …

YE Finnegan, AM Minihane, EC Leigh-Firbank… - The American journal of …, 2003 - Elsevier
Background: Dietary α-linolenic acid (ALA) can be converted to long-chain n− 3
polyunsaturated fatty acids (PUFAs) in humans and may reproduce some of the beneficial …

Plant and marine derived (n-3) polyunsaturated fatty acids do not affect blood coagulation and fibrinolytic factors in moderately hyperlipidemic humans.

YE Finnegan, D Howarth, AM Minihane… - The Journal of …, 2003 - europepmc.org
Dietary alpha-linolenic acid (ALA) can be converted to long-chain (n-3) PUFA in humans
and may potentially reproduce the beneficial effects of eicosapentaenoic (EPA) and …

Antihypertensive effect and safety of dietary α-linolenic acid in subjects with high-normal blood pressure and mild hypertension

H Takeuchi, C Sakurai, R Noda, S Sekine… - Journal of Oleo …, 2007 - jstage.jst.go.jp
We investigated the antihypertensive effect and safety of α-linolenic acid (ALA) in human
subjects. In Experiment 1, subjects with high-normal blood pressure and mild hypertension …