At least 10% of patients with pulmonary fibrosis, whether idiopathic or secondary, present
heritable pulmonary fibrosis suspected on familial aggregation of pulmonary fibrosis …

At least 10% of patients with interstitial lung disease present monogenic lung fibrosis
suspected on familial aggregation of pulmonary fibrosis, specific syndromes or early age of …

The genetic causes of interstitial lung disease (ILD) are predominantly evidenced in
telomere related genes (TRG) and surfactant related genes (SRG). SRG are associated with …

Genetic sequence variants have been linked to familial pulmonary fibrosis (FPF). Many of
the same genetic mechanisms implicated in FPF are relevant to sporadic interstitial lung …

The inherited risk for pulmonary fibrosis is substantial, and recent data suggests that genetic
risk for familial and sporadic forms of the disease are similar. Further characterization of the …

Pulmonary fibrosis comprises a wide range of fibrotic lung diseases with unknown
pathogenesis and poor prognosis. Familial pulmonary fibrosis (FPF) represents a unique …

There is clear evidence that environmental exposures and genetic predisposition contribute
to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Cigarette smoking increases the …

Interstitial lung diseases encompass a wide range of diffuse lung disorders that are often
complicated by the development of pulmonary fibrosis and that can occur in isolation or in …

The occurrence of pulmonary fibrosis in numerous individuals from the same family
suggests a genetic cause for the disease. During the last 10 years, mutations involving …

Idiopathic pulmonary fibrosis is a chronic interstitial lung disease of unknown cause. In the
past years there have been observations of clustering of pulmonary fibrosis in families …