[HTML][HTML] Development of therapeutic vaccines for ovarian cancer

S Chow, JS Berek, O Dorigo - Vaccines, 2020 - mdpi.com
Ovarian cancer remains the deadliest of all gynecologic malignancies. Our expanding
knowledge of ovarian cancer immunology has allowed the development of therapies that …

Therapeutic vaccines for ovarian cancer

JB Liao, ML Disis - Gynecologic oncology, 2013 - Elsevier
While therapeutic vaccines for ovarian cancer represent only a small fraction of active
clinical trials, growing interest in this area and the accumulated data supporting the use of …

Vaccine-based clinical trials in ovarian cancer

N Leffers, T Daemen, HM Boezen… - Expert review of …, 2011 - Taylor & Francis
Ovarian cancer vaccines are one of the new treatment strategies under investigation in
epithelial ovarian cancer. This article discusses the results of different immunization …

[HTML][HTML] Cancer vaccines in ovarian cancer: how can we improve?

S Martin Lluesma, A Wolfer, A Harari, LE Kandalaft - Biomedicines, 2016 - mdpi.com
Epithelial ovarian cancer (EOC) is one important cause of gynecologic cancer-related death.
Currently, the mainstay of ovarian cancer treatment consists of cytoreductive surgery and …

Immunotherapy opportunities in ovarian cancer

CS Chu, SH Kim, CH June… - Expert review of anticancer …, 2008 - Taylor & Francis
Ovarian cancer is responsible for the majority of gynecologic cancer deaths and despite the
highest standard of multimodality therapy with surgery and cytotoxic chemotherapy, long …

Dendritic cell-based tumor vaccinations in epithelial ovarian cancer: a systematic review

JL Tanyi, CS Chu - Immunotherapy, 2012 - Future Medicine
After decades of extensive research, epithelial ovarian cancer still remains a lethal disease.
Multiple new studies have reported that the immune system plays a critical role in the growth …

General keynote: vaccine strategies for the therapy of ovarian cancer

JW Hodge, KY Tsang, DJ Poole, J Schlom - Gynecologic oncology, 2003 - Elsevier
Epithelial carcinoma of the ovary is one of the most common gynecologic malignancies and
the fifth most frequent cause of cancer death in women [1]. Malignant ovarian tumors are the …

[HTML][HTML] Integrating cancer vaccines in the standard-of-care of ovarian cancer: translating preclinical models to human

CLL Chiang, R Rovelli, A Sarivalasis, LE Kandalaft - Cancers, 2021 - mdpi.com
Simple Summary The overall survival of ovarian cancer (OC) remains poor for most patients.
Despite incorporation of novel therapeutic agents such as bevacizumab and PARP …

Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer

JL Tanyi, S Bobisse, E Ophir, S Tuyaerts… - Science translational …, 2018 - science.org
We conducted a pilot clinical trial testing a personalized vaccine generated by autologous
dendritic cells (DCs) pulsed with oxidized autologous whole-tumor cell lysate (OCDC) …

[HTML][HTML] Personalized dendritic cell vaccines—recent breakthroughs and encouraging clinical results

B Mastelic-Gavillet, K Balint, C Boudousquie… - Frontiers in …, 2019 - frontiersin.org
With the advent of combined immunotherapies, personalized dendritic cell (DC)-based
vaccination could integrate the current standard of care for the treatment of a large variety of …