New perspectives in antiplatelet therapy

A Tello-Montoliu, E Jover, J Rivera… - Current medicinal …, 2012 - ingentaconnect.com
Platelet activation is a complex mechanism of response to vascular injury and
atherothrombotic disease, leading to thrombus formation. A wide variety of surface receptors …

[HTML][HTML] Progress in the development of antiplatelet agents: Focus on the targeted molecular pathway from bench to clinic

Q Xiang, X Pang, Z Liu, G Yang, W Tao, Q Pei… - Pharmacology & …, 2019 - Elsevier
Antiplatelet drugs serve as a first-line antithrombotic therapy for the management of acute
ischemic events and the prevention of secondary complications in vascular diseases …

[HTML][HTML] Antiplatelet therapy—A pharmacologist's perspective

J Bultas - Cor et Vasa, 2013 - Elsevier
There are only few areas of cardiology that have witnessed such dramatic innovations as
that occurring in the treatment and prophylaxis of thrombotic events. Antithrombotic (ie …

[PDF][PDF] Antiplatelet therapy: present status and its future directions

K Ahluwalia, S Bhanwra - Int J Basic Clin Pharmacol, 2014 - academia.edu
Anti-platelets drugs play an important role in the prevention or treatment of cardiovascular
diseases eg coronary artery disease, stroke, etc., which cause high mortality and morbidity …

Strategies for antiplatelet targets and agents

YZ Xiang, LY Kang, XM Gao, HC Shang, JH Zhang… - Thrombosis research, 2008 - Elsevier
Platelets play a key role in thrombosis and haemostasis, which can be either beneficial or
deleterious depending on the circumstance. Antiplatelet therapy is the 'cornerstone'in the …

Platelet activation, and antiplatelet targets and agents: current and novel strategies

YZ Xiang, Y Xia, XM Gao, HC Shang, LY Kang… - Drugs, 2008 - Springer
Platelets play a key role in thrombosis and haemostasis, which can be either beneficial or
deleterious depending on the circumstances. Multiple factors, such as genetic …

Pharmacology of antiplatelet agents

K Kalra, CJ Franzese, MG Gesheff, EI Lev… - Current atherosclerosis …, 2013 - Springer
Pharmacotherapies with agents that inhibit platelet function have proven to be effective in
the treatment of acute coronary syndromes, and in the prevention of complications during …

New antiplatelet agents

G Spectre, D Varon - Current opinion in hematology, 2009 - journals.lww.com
Recent development of new antiplatelet agents, including inhibitors of thrombin receptor,
thromboxane receptor, phosphodiesterase, glycoprotein VI, GPIIbIIIa and signaling …

Future innovations in anti‐platelet therapies

NE Barrett, L Holbrook, S Jones… - British journal of …, 2008 - Wiley Online Library
Platelets have long been recognized to be of central importance in haemostasis, but their
participation in pathological conditions such as thrombosis, atherosclerosis and …

Clinical pharmacology of antiplatelet drugs

G Gelbenegger, B Jilma - Expert Review of Clinical Pharmacology, 2022 - Taylor & Francis
Introduction Platelets play a key role in arterial thrombosis and antiplatelet therapy is pivotal
in the treatment of cardiovascular disease. Current antiplatelet drugs target different …