Sleep disorders are prevalent in Alzheimer's disease (AD) and a major cause of
institutionalization. Like AD pathology, sleep abnormalities can appear years before …

As we age, we experience changes in our nighttime sleep and daytime wakefulness.
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …

Factors other than age and genetics may increase the risk of developing Alzheimer disease
(AD). Accumulation of the amyloid-β (Aβ) peptide in the brain seems to initiate a cascade of …

Disturbances of the sleep/wake cycle in Alzheimer's disease (AD) are common, frequently
precede cognitive decline, and tend to worsen with disease progression. Sleep is critical to …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline that is a growing public health crisis with a prevalence projected to more …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by an
asymptomatic period of amyloid-β (Aβ) deposition as insoluble extracellular plaque …

As we age, sleep patterns undergo significant modifications in micro and macrostructure,
worsening cognition and quality of life. These are associated with remarkable brain …

Sleep disturbances are routinely encountered in Alzheimer's disease (AD) and affect about
25–40% of patients in the mild-to-moderate stages of the disease. In many, sleep pathology …

Sleep–wake disturbances are a highly prevalent and often disabling feature of Alzheimer's
disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated …

Sleep disturbances, as well as sleep-wake rhythm disturbances, are typical symptoms of
Alzheimer's disease (AD) that may precede the other clinical signs of this neurodegenerative …