Background Exposure to airborne allergens is a frequent trigger of respiratory allergy and
asthma in atopic individuals. While allergic patients suffer hypersensitivity reactions to these …

Mouse allergy has become increasingly common, mainly affecting laboratory workers and
inner-city households. To date, only one major allergen, namely Mus m 1, has been …

BACKGROUND: The role of natural aeroallergen exposure in modulating allergen-specific
immune responses is not well understood. OBJECTIVE: We sought to examine relationships …

Background Evidence suggests that specific allergen sensitizations are associated with
different allergic diseases which may reflect different underlying immune profiles. We aimed …

Understanding the mechanisms of allergen-specific immune modulation in nonallergic
individuals is key to recapitulate immune tolerance and to develop novel allergy treatments …

Background High levels of allergen‐specific IgG have been associated with clinical efficacy
in immunotherapy studies, but whether this antibody isotype is associated with clinical …

A panel of 133 allergens derived from 28 different sources, including fungi, trees, grasses,
weeds, and indoor allergens, was surveyed utilizing prediction of HLA class II-binding …

To cite this article: Krop EJM, van de Pol MA, Lutter R, Heederik DJJ, Aalberse RC, van der
Zee JS. Dynamics in cytokine responses during the development of occupational …

Background. Regulatory T cells (Tregs) are important in regulating responses to innocuous
antigens, such as allergens, by controlling the Th2 response, a mechanism that appears to …

BACKGROUND: Although there is evidence that contact with mice is associated with IgE-
mediated mouse sensitization and mouse specific antibody responses, the …