[PDF][PDF] Atherosclerosis: pathophysiology of insulin resistance, hyperglycemia, hyperlipidemia, and inflammation

JK Beverly, MJ Budoff - Journal of diabetes, 2020 - escholarship.org
Atherosclerotic cardiovascular disease is on course to surpass infectious diseases as the
leading cause of morbidity and mortality worldwide. 6 Multiple risk factors are responsible for …

[引用][C] Do atherosclerosis and type 2 diabetes share a common inflammatory basis?

AD Pradhan, PM Ridker - European heart journal, 2002 - academic.oup.com
The number of adults with diagnosed type 2 diabetes worldwide will grow from 135 million in
1995 to approximately 300 million in 2025 [1]. Rapid acculturation to Western lifestyles …

Type 2 diabetes as an inflammatory cardiovascular disorder

D Ziegler - Current molecular medicine, 2005 - ingentaconnect.com
Type 2 diabetes carries a 2-6-fold increased risk of cardiovascular disease (CVD) and
death. Indeed, the risk of major cardiovascular events in Type 2 diabetic patients without …

The mystery of diabetes and atherosclerosis: time for a new plot

CF Semenkovich, JW Heinecke - Diabetes, 1997 - Am Diabetes Assoc
Most patients with diabetes die from macrovascular complications. Little is known about the
pathogenesis of diabetic vascular disease, but recent advances in molecular genetics and …

Molecular mechanisms linking diabetes to the accelerated development of atherosclerosis

MG Zeadin, CI Petlura, GH Werstuck - Canadian journal of diabetes, 2013 - Elsevier
Diabetes mellitus is a major independent risk factor for the development of cardiovascular
disease, and both type 1 and type 2 diabetes have been shown to accelerate the …

Type 2 diabetes: one disease, multiple cardiovascular risk factors

J Calles-Escandon, E Garcia-Rubi, S Mirza… - Coronary artery …, 1999 - journals.lww.com
Type 2 diabetes mellitus is a major independent risk factor for coronary artery disease.
Atherosclerosis accounts for about 80% of all deaths from type 2 diabetes, of which roughly …

Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies

T Mazzone, A Chait, J Plutzky - The Lancet, 2008 - thelancet.com
Individuals with type 2 diabetes mellitus have increased cardiovascular disease risk
compared with those without diabetes. Treatment of the residual risk, other than blood …

[HTML][HTML] Insulin resistance, hyperglycemia, and atherosclerosis

KE Bornfeldt, I Tabas - Cell metabolism, 2011 - cell.com
Progress in preventing atherosclerotic coronary artery disease (CAD) has been stalled by
the epidemic of type 2 diabetes. Further advances in this area demand a thorough …

Correlation between cardiovascular disease and diabetes mellitus: current concepts

RW Nesto - The American journal of medicine, 2004 - Elsevier
Individuals exhibiting precursor symptoms of diabetes mellitus or reaching diagnostic
thresholds for diabetes are at increased risk of death due to cardiovascular disease (CVD) …

The union of vascular and metabolic actions of insulin in sickness and in health

J Kim, KK Koh, MJ Quon - Arteriosclerosis, thrombosis, and …, 2005 - Am Heart Assoc
Disorders of metabolic homeostasis including type 2 diabetes, obesity, and dyslipidemias
are characterized by both insulin resistance and endothelial dysfunction. 1 Insulin resistance …