Antioxidant supplementation of mouse embryo culture or vitrification media support more in-vivo-like gene expression post-transfer
T Truong, AJ Harvey, DK Gardner - Reproductive BioMedicine Online, 2022 - Elsevier
Research question What is the effect on mouse fetal gene expression of combined
antioxidants (acetyl-L-carnitine, N-acetyl-L-cysteine and alpha-lipoic acid; A3) when used in …
antioxidants (acetyl-L-carnitine, N-acetyl-L-cysteine and alpha-lipoic acid; A3) when used in …
Antioxidants increase blastocyst cryosurvival and viability post-vitrification
TT Truong, DK Gardner - Human reproduction, 2020 - academic.oup.com
STUDY QUESTION What is the effect of antioxidants acetyl-L-carnitine, N-acetyl-L-cysteine
and α-lipoic acid (A3) in vitrification and warming solutions on mouse blastocyst …
and α-lipoic acid (A3) in vitrification and warming solutions on mouse blastocyst …
Antioxidants improve mouse preimplantation embryo development and viability
TT Truong, YM Soh, DK Gardner - Human Reproduction, 2016 - academic.oup.com
STUDY QUESTION What is the effect of three antioxidants (acetyl-L-carnitine, N-acetyl-L-
cysteine and α-lipoic acid), when used individually and in combination, on mouse embryo …
cysteine and α-lipoic acid), when used individually and in combination, on mouse embryo …
Oocyte Vitrification temporarily turns on oxidation-reduction process genes in mouse preimplantation embryos
G Ruihuan, L Zhichao, G Song, F Jing, S Yijuan… - Reproductive …, 2021 - Springer
We aim to understand how oocyte vitrification impacts subsequent mouse preimplantation
embryo development at molecular level. We profiled transcriptomics of fertilized …
embryo development at molecular level. We profiled transcriptomics of fertilized …
Antioxidant supplementation of culture medium during embryo development and/or after vitrification-warming; which is the most important?
Purpose To determine the most optimal stage for antioxidant supplementation of culture
medium to improve developmental competence, cryotolerance and DNA-fragmentation of …
medium to improve developmental competence, cryotolerance and DNA-fragmentation of …
O-235 Antioxidants in culture media improve ICSI fertilisation rate: results from a randomised controlled trial
Study question Does addition of three antioxidants to G-Series media during gamete
collection, insemination, and embryo culture increase the clinical pregnancy rate from fresh …
collection, insemination, and embryo culture increase the clinical pregnancy rate from fresh …
Antioxidants improve IVF outcome and subsequent embryo development in the mouse
T Truong, DK Gardner - Human Reproduction, 2017 - academic.oup.com
STUDY QUESTION What is the effect of a combination of three antioxidants (Acetyl-L-
Carnitine, N-Acetyl-L-Cysteine and α-Lipoic Acid), present in IVF medium during mouse …
Carnitine, N-Acetyl-L-Cysteine and α-Lipoic Acid), present in IVF medium during mouse …
Supplementing culture and vitrification-warming media with l-ascorbic acid enhances survival rates and redox status of IVP porcine blastocysts via induction of GPX1 …
M Castillo-Martín, S Bonet, R Morató, M Yeste - Cryobiology, 2014 - Elsevier
The present study sought to determine the effect of adding l-ascorbic acid (AC) to (1) in vitro
culture medium and (2) vitrification and warming solutions on redox status and …
culture medium and (2) vitrification and warming solutions on redox status and …
Exogenous L-glutathione improves vitrification outcomes in murine preimplantation embryos
Vitrification is an important tool to store surplus embryos in assisted reproductive technology
(ART). However, vitrification increases oxidative damage and results in decreased viability …
(ART). However, vitrification increases oxidative damage and results in decreased viability …
Antioxidant supplementation during in vitro culture improves mitochondrial function and development of embryos from aged female mice
E Silva, AF Greene, K Strauss, JR Herrick… - Reproduction …, 2015 - CSIRO Publishing
Maternal aging results in reduced oocyte and blastocyst quality, thought to be due, in part, to
mitochondrial dysfunction and accumulation of reactive oxygen species. To reduce oxidative …
mitochondrial dysfunction and accumulation of reactive oxygen species. To reduce oxidative …