NOD-like receptors (NLRs) are a class of cytoplasmic pattern-recognition receptors.
Although most NLRs play some role in immunity, their functions range from regulating …

Nod-like receptors (NLRs) are intracellular sentinel proteins that are implicated in the
detection of microbes and danger signals, thereby controlling several key innate immune …

NLRC5 is a member of the NLR family that acts as a transcriptional activator of MHC class I
genes. In line with the function of several related NLR proteins in innate immune responses …

Nod-like receptors (NLRs) are intracellular sensors that respond to a variety of pathogen
and intracellular danger signals to induce innate immune responses. NLRC5 has recently …

The nucleotide-binding oligomerization domain-like receptor (NLR) family member, Nlrp6,
has been implicated in inflammasome signaling to activate caspase-1, which is essential for …

NLRP6, a member of the nucleotide-binding domain, leucine-rich repeat-containing (NLR)
innate immune receptor family, regulates inflammation and host defense against …

Appropriate immune responses require a fine balance between immune activation and
attenuation. NLRC3, a non-inflammasome-forming member of the NLR innate immune …

The NOD like receptors (NLRs), a class of intracellular receptors that respond to pathogen
attack or cellular stress, have gained increasing attention. NLRC5, the largest member of the …

Nucleotide-binding leucine-rich repeat-containing proteins, or NOD-like receptors (NLRs),
are intracellular innate immune sensors that can regulate several signaling pathways …

NLRs play fundamental roles in host-defense and inflammatory disorders. NLRP6 is a newly
characterized member of this family that inhibits NF-κB and MAP-kinase dependent immune …