Antihyperalgesic activities of endocannabinoids in a mouse model of antiretroviral-induced neuropathic pain

N Munawar, MA Oriowo, W Masocha - Frontiers in pharmacology, 2017 - frontiersin.org
Background: Nucleoside reverse transcriptase inhibitors (NRTIs) are the cornerstone of the
antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency …

β-Caryophyllene, a CB2-receptor-selective phytocannabinoid, suppresses mechanical allodynia in a mouse model of antiretroviral-induced neuropathic pain

E Aly, MA Khajah, W Masocha - Molecules, 2019 - mdpi.com
Neuropathic pain associated with nucleoside reverse transcriptase inhibitors (NRTIs),
therapeutic agents for human immunodeficiency virus (HIV), responds poorly to available …

[HTML][HTML] Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: a systematic review

E Aly, W Masocha - IBRO neuroscience reports, 2021 - Elsevier
Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently
induce HIV-associated neuropathic pain (HIV-NP). There is a dearth of drugs or therapeutic …

Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection‐Induced Neuropathic Pain

WS Sheng, P Chauhan, S Hu, S Prasad… - Pain Research and …, 2019 - Wiley Online Library
The most common neurological complication in patients receiving successful combination
antiretroviral therapy (cART) is peripheral neuropathic pain. Data show that distal symmetric …

Blockade of the spinal BDNF-activated JNK pathway prevents the development of antiretroviral-induced neuropathic pain

MD Sanna, C Ghelardini, N Galeotti - Neuropharmacology, 2016 - Elsevier
Although antiretroviral agents have been used successfully in suppressing viral production,
they have also been associated with a number of side effects. The antiretroviral toxic …

Peripheral sensory neuron CB2 cannabinoid receptors are necessary for both CB2-mediated antinociceptive efficacy and sparing of morphine tolerance in a mouse …

LM Carey, Z Xu, G Rajic, A Makriyannis… - Pharmacological …, 2023 - Elsevier
Painful peripheral neuropathy is a common neurological complication associated with
human immunodeficiency virus (HIV) infection and anti-retroviral therapy. We characterized …

[HTML][HTML] Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors …

W Masocha, A Thomas - Journal of Pharmacological Sciences, 2019 - Elsevier
Neuropathic pain sometimes occurs during chemotherapy with paclitaxel or HIV/AIDS
antiretroviral therapy with nucleoside reverse transcriptase inhibitors (NRTIs). We previously …

Alcohol consumption enhances antiretroviral painful peripheral neuropathy by mitochondrial mechanisms

LF Ferrari, JD Levine - European Journal of Neuroscience, 2010 - Wiley Online Library
A major dose‐limiting side effect of human immunodeficiency virus/acquired
immunodeficiency syndrome (HIV/AIDS) chemotherapies, such as the nucleoside reverse …

Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of …

MV Noya-Riobó, CÁ Miguel, DB Soriano… - Experimental …, 2023 - Elsevier
Chemotherapy-induced neuropathic pain is a serious clinical problem and one of the major
side effects in cancer treatment. The endocannabinoid system (ECS) plays a crucial role in …

[PDF][PDF] The effect of smoked marijuana on chronic neuropathic and experimentally induced pain in HIV neuropathy: Results of an open-label pilot study

C Jay, S Shade, H Vizoso, H Reda… - Int Conf Retroviruses …, 2004 - researchgate.net
BACKGROUND Background: Painful peripheral neuropathy continues to be a significant
clinical problem in patients (pts) with HIV infection. Preclinical studies suggest that …