[HTML][HTML] Revolutionizing cancer treatment: the power of bi-and tri-specific T-cell engagers in oncolytic virotherapy
AZ Mehrabadi, M Tat, AG Alvanegh… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Bi-or tri-specific T cell engagers (BiTE or TriTE) are recombinant bispecific proteins
designed to stimulate T-cell immunity directly, bypassing antigen presentation by antigen …
designed to stimulate T-cell immunity directly, bypassing antigen presentation by antigen …
[HTML][HTML] Revolutionizing cancer treatment: the power of bi-and tri-specific T-cell engagers in oncolytic virotherapy
A Zarezadeh Mehrabadi, M Tat… - Frontiers in …, 2024 - frontiersin.org
Bi-or tri-specific T cell engagers (BiTE or TriTE) are recombinant bispecific proteins
designed to stimulate T-cell immunity directly, bypassing antigen presentation by antigen …
designed to stimulate T-cell immunity directly, bypassing antigen presentation by antigen …
[HTML][HTML] Oncolytic viruses encoding bispecific T cell engagers: a blueprint for emerging immunovirotherapies
JPW Heidbuechel, CE Engeland - Journal of hematology & oncology, 2021 - Springer
Bispecific T cell engagers (BiTEs) are an innovative class of immunotherapeutics that
redirect T cells to tumor surface antigens. While efficacious against certain hematological …
redirect T cells to tumor surface antigens. While efficacious against certain hematological …
[HTML][HTML] Bi-and tri-specific T cell engager-armed oncolytic viruses: next-generation cancer immunotherapy
Oncolytic viruses (OVs) are potent anti-cancer biologics with a bright future, having
substantial evidence of efficacy in patients with cancer. Bi-and tri-specific antibodies …
substantial evidence of efficacy in patients with cancer. Bi-and tri-specific antibodies …
Arming oncolytic viruses with bispecific T cell engagers: The evolution and current status
Y Wang, P Cheng - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2023 - Elsevier
Oncolytic viruses (OVs) are emerging as therapeutically relevant anticancer agents as
contemporary immunotherapy gains traction. Furthermore, OVs are an ideal platform for …
contemporary immunotherapy gains traction. Furthermore, OVs are an ideal platform for …
[HTML][HTML] Bispecific T cell engagers and their synergistic tumor immunotherapy with oncolytic viruses
Q Huang, WQ Cai, ZW Han, MY Wang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Tumor immunotherapy, especially T cell based therapy, is becoming the main force in
clinical tumor therapies. Bispecific T cell engager (BiTE) uses the single chain variable …
clinical tumor therapies. Bispecific T cell engager (BiTE) uses the single chain variable …
Solid tumor immunotherapy with T cell engager‐armed oncolytic viruses
EM Scott, MR Duffy, JD Freedman… - Macromolecular …, 2018 - Wiley Online Library
Oncolytic viruses (OVs) are novel anticancer agents that combine direct cancer cell killing
with the stimulation of antitumor immunity. In addition, OVs can be engineered to deliver …
with the stimulation of antitumor immunity. In addition, OVs can be engineered to deliver …
Bispecific T‐cell engagers for cancer immunotherapy
AM Huehls, TA Coupet… - Immunology and cell …, 2015 - Wiley Online Library
Bispecific T‐cell engagers (BiTEs) are a new class of immunotherapeutic molecules
intended for the treatment of cancer. These molecules enhance the patient's immune …
intended for the treatment of cancer. These molecules enhance the patient's immune …
[HTML][HTML] Oncolytic virotherapy evolved into the fourth generation as tumor immunotherapy
X Wang, Y Shen, X Wan, X Hu, WQ Cai, Z Wu… - Journal of Translational …, 2023 - Springer
Background Oncolytic virotherapy (OVT) is a promising anti-tumor modality that utilizes
oncolytic viruses (OVs) to preferentially attack cancers rather than normal tissues. With the …
oncolytic viruses (OVs) to preferentially attack cancers rather than normal tissues. With the …
[HTML][HTML] Improved anti-leukemia activities of adoptively transferred T cells expressing bites
Bispecific T cell engagers (BiTEs) that are specific for both a surface target antigen on
cancer cells and CD3 on T cells have been used to engage T cells for cancer therapies …
cancer cells and CD3 on T cells have been used to engage T cells for cancer therapies …