Grey matter morphometric biomarkers for classifying early schizophrenia and PD psychosis: a multicentre study

F Knolle, SS Arumugham, RA Barker, MWL Chee… - medRxiv, 2022 - medrxiv.org
Background Psychotic symptoms occur in a majority of schizophrenia patients, and in
approximately 50% of all Parkinson's disease (PD) patients. Altered grey matter (GM) …

[HTML][HTML] A multicentre study on grey matter morphometric biomarkers for classifying early schizophrenia and parkinson's disease psychosis

F Knolle, SS Arumugham, RA Barker… - npj Parkinson's …, 2023 - nature.com
Psychotic symptoms occur in a majority of schizophrenia patients and in~ 50% of all
Parkinson's disease (PD) patients. Altered grey matter (GM) structure within several brain …

[HTML][HTML] Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder

E Schwarz, NT Doan, G Pergola, LT Westlye… - Translational …, 2019 - nature.com
Schizophrenia is a severe mental disorder characterized by numerous subtle changes in
brain structure and function. Machine learning allows exploring the utility of combining …

[HTML][HTML] Brain function, structure and genomic data are linked but show different sensitivity to duration of illness and disease stage in schizophrenia

N Luo, L Tian, VD Calhoun, J Chen, D Lin… - NeuroImage: Clinical, 2019 - Elsevier
The progress of schizophrenia at various stages is an intriguing question, which has been
explored to some degree using single-modality brain imaging data, eg gray matter (GM) or …

First-episode psychosis: Structural covariance deficits in salience network correlate with symptoms severity

F Saviola, M Bellani, C Perlini, L Squarcina… - Journal of Psychiatric …, 2021 - Elsevier
Background Patterns of coordinated variations of gray matter (GM) morphology across
individuals are promising indicators of disease. However, it remains unclear if they can help …

Identifying grey matter changes in schizotypy using partial least squares correlation

K Wiebels, KE Waldie, RP Roberts, HRP Park - Cortex, 2016 - Elsevier
Neuroimaging research into the brain structure of schizophrenia patients has shown
consistent reductions in grey matter volume relative to healthy controls. Examining structural …

Classifying schizophrenia using multimodal multivariate pattern recognition analysis: evaluating the impact of individual clinical profiles on the neurodiagnostic …

C Cabral, L Kambeitz-Ilankovic, J Kambeitz… - Schizophrenia …, 2016 - academic.oup.com
Previous studies have shown that structural brain changes are among the best-studied
candidate markers for schizophrenia (SZ) along with functional connectivity (FC) alterations …

[HTML][HTML] Network constraints on longitudinal grey matter changes in first episode psychosis

S Chopra, S Oldham, A Segal, A Holmes… - medRxiv, 2022 - medrxiv.org
Background Different regions of the brain's grey matter are connected by a complex
structural network of white matter fibres, which are responsible for the propagation of action …

[HTML][HTML] Grey matter connectome abnormalities and age-related effects in antipsychotic-naive schizophrenia

B Yang, W Zhang, R Lencer, B Tao, B Tang, J Yang… - …, 2021 - thelancet.com
Background Convergent evidence is increasing to indicate progressive brain abnormalities
in schizophrenia. Knowing the brain network features over the illness course in …

[HTML][HTML] Updating and characterizing neuroanatomical markers in high-risk subjects, recently diagnosed and chronic patients with schizophrenia: A revised coordinate …

D Liloia, C Brasso, F Cauda, L Mancuso, A Nani… - Neuroscience & …, 2021 - Elsevier
Characterizing neuroanatomical markers of different stages of schizophrenia (SZ) to assess
pathophysiological models of how the disorder develops is an important target for the …