Conspectus Defining the two-dimensional structure of cell membranes represents one of the
most daunting challenges currently facing chemists, biochemists, and biophysicists. In …

Lipid raft/domain formation may arise as a result of the effects of specific sterols on the
physical properties of membranes. Here, using molecular dynamics simulation, we examine …

The fundamental role of cholesterol in the regulation of eukaryotic membrane structure is
well-established. However the manner in which atomic level interactions between …

The plasma membrane, which encapsulates human cells, is composed of a complex mixture
of lipids and embedded proteins. Emerging knowledge points towards the lipids as having a …

Cholesterol molecules were put into a computer-modeled hydrated bilayer of dimyristoyl
phosphatidyl choline molecules, and molecular dynamics simulations were run to …

Cholesterol is an important component of eukaryotic cellular membranes. Despite extensive
literature on the physiochemical effects of cholesterol on membranes, much remains …

In recent years, a massive increase has been observed in the number of published articles
describing accurate and reliable molecular dynamics simulations of lipid bilayers. This is …

Cholesterol suppresses the hemolysis and the detachment of cytoskeletal proteins from
bilayer in the human erythrocyte membrane under stress conditions. However, there is little …

We have used a spin label analog of cholesterol bearing a nitroxide on the alkyl chain (26-
nor-25-doxylcholestanol) to study cholesterol-protein interactions in the human erythrocyte …

Peroxidation of plasma membranes, characterized by oxidative attack of lipidic carbon–
carbon double-bonds in unsaturated fatty acids, has been identified as an important …