Immunoprotective effects of DNA vaccine against Eimeria tenella based on EtAMA3 and EtRON2L2

X Chen, X Qiu, J Ni, S Liao, N Qi, J Li, M Lv, X Lin… - Veterinary …, 2024 - Elsevier
Eimeria tenella is the most pathogenic and harmful intestinal parasitic protozoan.
Recombinant DNA vaccines open options for promising strategies for preventing avian …

Identification and Characterization of Eimeria tenella Rhoptry Protein 35 (EtROP35)

B Wang, N Zhao, J Sun, L Sun, H Li, Z Wu, H Li… - Veterinary …, 2022 - mdpi.com
Simple Summary Rhoptry proteins (ROPs) of phylum Apicomplexa parasites are important
secretory virulence factors as well as candidate vaccines. However, studies on ROPs of …

Improving the immunogenicity and protective efficacy of the EtMIC2 protein against Eimeria tenella infection through random mutagenesis

Z Chen, X Wang, N Zhao, L Han, F Wang, H Li, Y Cui… - Vaccine, 2018 - Elsevier
In recent years, directed evolution has emerged as an efficient tool to develop and identify
novel protein variants. Eimeria tenella microneme-2 (EtMIC2) is a promising vaccine …

Eimeria tenella Eimeria-specific protein that interacts with apical membrane antigen 1 (EtAMA1) is involved in host cell invasion

C Li, Q Zhao, S Zhu, Q Wang, H Wang, S Yu, Y Yu… - Parasites & …, 2020 - Springer
Background Avian coccidiosis is a widespread, economically significant disease of poultry,
caused by several Eimeria species. These parasites have complex and diverse life-cycles …

Recombinant lactococcus lactis expressing Eimeria tenella AMA1 protein and its immunological effects against homologous challenge

J Li, F Wang, C Ma, Y Huang, D Wang, D Ma - Experimental parasitology, 2018 - Elsevier
Avian coccidiosis leads to severe economic losses for the global poultry industry. Apical
membrane antigen 1 (AMA1) of E. tenella (EtAMA1) plays a vital role during invasion of …

Pichia pastoris expressed EtMic2 protein as a potential vaccine against chicken coccidiosis

J Zhang, P Chen, H Sun, Q Liu, L Wang, T Wang… - Veterinary …, 2014 - Elsevier
Chicken coccidiosis caused by Eimeria species leads to tremendous economic losses to the
avian industry worldwide. Identification of parasite life cycle specific antigens is a critical step …

[HTML][HTML] Molecular characterization and immune protective efficacy of 3 Eimeria tenella antigens

L Zhang, Z Song, P Li, X Song, X Tang, D Hu - Poultry Science, 2024 - Elsevier
Avian coccidiosis caused by Eimeria is a serious parasitic disease that poses a threat to the
poultry industry. Currently, prevention and treatment mainly rely on the administration of …

[HTML][HTML] Molecular characterization and protective efficacy of a new conserved hypothetical protein of Eimeria tenella

H Zhao, S Zhu, Q Zhao, B Huang, G Liu, Z Li, L Wang… - Parasite, 2021 - ncbi.nlm.nih.gov
Eimeria tenella is an obligate intracellular parasite that actively invades cecal epithelial cells
of chickens. This parasite encodes a genome of more than 8000 genes. However, more than …

Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle

V Marugan-Hernandez, E Long, D Blake, C Crouch… - Scientific Reports, 2017 - nature.com
Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live
vaccines are available and the development of reverse genetic technologies has raised the …

In vivo immunoprotective comparison between recombinant protein and DNA vaccine of Eimeria tenella surface antigen 4

P Zhao, Y Li, Y Zhou, J Zhao, R Fang - Veterinary parasitology, 2020 - Elsevier
Eimeria tenella, belonging to protozoon, is the causative agent of cecal coccidiosis in
chicken and causes enormous impacts for poultry industry. The surface antigens of …