Construction of Eimeria tenella multi-epitope DNA vaccines and their protective efficacies against experimental infection

X Song, L Xu, R Yan, X Huang, X Li - Veterinary immunology and …, 2015 - Elsevier
The search for effective vaccines against chicken coccidiosis remains a challenge because
of the complex organisms with multiple life cycle stages of Eimeria. Combination of T-cell …

Eimeria tenella microneme protein EtMIC4: capture of the full-length transcribed sequence and comparison with other microneme proteins

J Periz, R Ryan, DP Blake, FM Tomley - Parasitology research, 2009 - Springer
EtMIC4 is a microneme protein of Eimeria tenella, an intracellular apicomplexan protozoan
that can cause severe enteritis in chickens. The EtMIC4 gene has been partially …

[HTML][HTML] Construction and Analysis of Coexpression Network to Understand Biological Responses in Chickens Infected by Eimeria tenella

B Liu, X Ma, J Cai - Frontiers in Veterinary Science, 2021 - frontiersin.org
Coccidiosis, caused by various Eimeria species, is a major parasitic disease in chickens.
Our understanding of how chickens respond to coccidian infections is highly limited at both …

Ultrastructural observations of development ofEimeria tenella in a novel established avian-derived cell line

HD Danforth, PC Augustine, RA Clare - Parasitology Research, 1994 - Springer
Transmission electron microscopy was used to study the in vitro development of Eimeria
tenella in a novel established avian-derived cell line (designated CEV-1/F7) used for …

Immunogenicity and protective efficacy of an Eimeria vaccine candidate based on Eimeria tenella immune mapped protein 1 and chicken CD40 ligand

G Yin, Q Lin, J Qiu, M Qin, X Tang, X Suo, Z Huang… - Veterinary …, 2015 - Elsevier
Abstract The CD40 ligand (CD40L) has shown potential as a powerful immunological
adjuvant in various studies. Here, the efficacy of a chimeric subunit vaccine, consisting of …

Identification and characterization of a cDNA clone-encoding antigen of Eimeria acervulina

H Zhu, L Xu, R Yan, X Song, F Tang, S Wang, X Li - Parasitology, 2012 - cambridge.org
Eimeria spp. are the causative agents of coccidiosis, a major disease affecting the poultry
industry. So far, only a few antigen genes of E. acervulina have been reported. In this study …

Protective immunity induced by Eimeria common antigen 14–3-3 against Eimeria tenella, Eimeria acervulina and Eimeria maxima

J Liu, L Liu, L Li, D Tian, W Li, L Xu, R Yan, X Li… - BMC Veterinary …, 2018 - Springer
Background Avian coccidiosis is often caused by co-infection with several species of
Eimeria worldwide. Developing a multivalent vaccine with an antigen common to multiple …

Characterization and immunoprotective properties of a monoclonal antibody against the major oocyst wall protein of Eimeria tenella

MJ Karim, SC Basak, AJ Trees - Infection and immunity, 1996 - Am Soc Microbiol
The oocyst wall of Eimeria spp. consists of a 10-nm-thick outer lipid layer and a 90-mm-thick
inner layer of glycoprotein which has been described previously to be composed of a single …

[HTML][HTML] Expression of host defense peptides in the intestine of Eimeria-challenged chickens

S Su, DM Dwyer, KB Miska, RH Fetterer, MC Jenkins… - Poultry Science, 2017 - Elsevier
Avian coccidiosis is caused by the intracellular protozoan Eimeria, which produces intestinal
lesions leading to weight gain depression. Current control methods include vaccination and …

Identification and characterization of a target antigen of a monoclonal antibody directed against Eimeria tenella merozoites

C Ko, CK Smith II, M McDonell - Molecular and biochemical parasitology, 1990 - Elsevier
Monoclonal antibodies (Mab) were produced against Eimeria tenella merozoites. A single
Mab, LPMC-61, was selected because of its ability to bind to merozoites by indirect …