Ovarian aging leads to a decrease in the quantity and quality of oocytes. Aged oocytes have
significantly reduced amounts of mitochondria, the energy factories of cells, leading to lower …

Older women are often the most challenging group of patients in fertility clinics due to a
decline in both number and overall quality of oocytes. The quality of oocytes has been linked …

Along with the decline in oocyte quality, numerous defects such as mitochondrial
insufficiency and the increase of mutation and deletion have been reported in oocyte …

Ovarian aging is characterized by a decline in both the total number and overall quality of
oocytes, the latter of which has been experimentally tied to mitochondrial dysfunction …

As the vital organelles for cell energy metabolism, mitochondria are essential for oocyte
maturation, fertilization, and embryo development. Abnormalities in quantity, quality, and …

The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Purpose The number of women attempting to conceive between the ages of 36 and 44 has
increased significantly in the last decade. While it is well established that women's …

Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte
quality which is important for fertilization and development into viable offspring. Quality …

In recent years, postponement of marriage and childbearing in women of reproductive age
has led to an increase in the incidence of age-related infertility. The reproductive aging …

The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …