Spinal cord injury (SCI) results in the development of chronic pain syndromes that can
persist indefinitely and cause reductions in quality of life. Treatment of chronic pain after SCI …

Traumatic spinal cord injury (SCI) results not only in motor impairment but also in chronic
central pain, which can be refractory to conventional treatment approaches. It has been …

Peripheral nerve injuries that provoke neuropathic pain are associated with microglial
activation in the spinal cord. We have investigated the characteristics of spinal microglial …

Microglia are the resident macrophages in the central nervous system (CNS). Any insult to
the CNS homeostasis will induce a rapid change in microglia morphology, gene expression …

The pharmacological attenuation of glial activation represents a novel approach for
controlling neuropathic pain, but the role of microglial and astroglial cells is not well …

Mounting evidence supports the hypothesis that spinal microglia modulate the development
and maintenance of some chronic pain states. Here we examined the role of spinal …

Spinal cord injury (SCI) is a debilitating condition that is frequently accompanied by
neuropathic pain, resulting in significant physical and psychological harm to a vast number …

Spinal cord injury (SCI) is known as a debilitating condition which usually occurs due to
traumas to the spine. However, the injury could also occur during clinical interventions such …

Neuropathic pain after spinal cord injury (SCI) is common, often intractable, and can be
severely debilitating. A number of mechanisms have been proposed for this pain, which are …

Spinal cord injury (SCI) impairs sensory systems causing chronic allodynia. Mechanisms
underlying neuropathic pain have been more extensively studied following peripheral nerve …