The RNA-binding protein HuR, a member of the embryonic lethal abnormal vision/Hu
protein family, plays a critical role in many cellular processes, including cell proliferation …

ABSTRACT P21, a cyclin-dependent kinase inhibitor, plays a pivotal role in the cell-cycle
regulation in response to stress stimuli. P21 expression is highly regulated through …

The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …

The RNA-binding protein HuR binds at 3′ untranslated regions (UTRs) of target transcripts,
thereby protecting them against degradation. We show that HuR directly interacts with …

Abstract Poly (ADP-ribosyl) ation (PARylation) is mainly catalysed by poly-ADP-ribose
polymerase 1 (PARP1), whose role in gene transcription modulation has been well …

The heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute an important group of
RNA-binding proteins (RBPs) that play an active role in post-transcriptional gene regulation …

A high expression level of the β-actin protein is required for important biological
mechanisms, such as maintaining cell shape, growth, and motility. Although the elevated …

The RNA-binding protein HuR (also known as ELAV1) binds to the 3′-untranslated region
of mRNAs and regulates transcript stability and translation. However, the in vivo functions of …

Overexpression of the messenger RNA (mRNA)-binding protein HuR is an important feature
of many tumors and in most cases correlates with a high-grade malignancy. Since …

The RNA‐binding protein HuR promotes tumor growth by affecting proliferation, metastasis,
apoptosis, and angiogenesis. Although immune cells, especially tumor‐associated …