G-Quadruplexes (G4s) are ubiquitous nucleic acid folding motifs that exhibit structural
diversity that is dependent on cationic conditions. In this work, we exploit temperature …

G-quadruplexes adopt various folding topologies, but information on their folding pathways
remains scarce. Here, we used electrospray mass spectrometry to detect and quantify the …

Abstract G-quadruplexes (G4s) are non-canonical nucleic acid structures that fold through
complex processes. Characterization of the G4 folding landscape may help to elucidate …

Numerous studies have reported cation-dependent stability and topological changes of G-
quadruplexes (G4s), but competitions between cations at different concentrations for binding …

The folding kinetics is an important parameter affecting the relevance of DNA and RNA G-
quadruplex (G4) structures in biological processes. Previous studies of the G4 folding …

DNA G-quadruplexes are essential motifs in molecular biology performing a wide range of
functions enabled by their unique and diverse structures. In this study, we focus on the …

Telomeric DNA sequences are particularly polymorphic: the adopted structure is exquisitely
sensitive to the sequence and to the chemical environment, for example, solvation …

G-quadruplexes are a highly studied DNA motif with a potential role in a variety of cellular
processes and more recently are considered novel targets for drug therapy in aging and …

G-quadruplexes (G4s) are secondary structures formed by guanine-rich oligonucleotides
involved in various biological processes. However, characterizing G4s is challenging …

A human telomere sequence that folds into an intramolecular (3+ 1)-hybrid G-quadruplex
was modified by the incorporation of 2′-fluoro-2′-deoxyriboguanosines (FG) into syn …