Immuno-SPECT/PET imaging with radioiodinated anti-PD-L1 antibody to evaluate PD-L1 expression in immune-competent murine models and PDX model of lung …

X Wen, C Shi, L Zhao, L Yao, D Xu, X Lin, X Su… - Nuclear Medicine and …, 2020 - Elsevier
Objective Accurate evaluation of tumor programmed death ligand 1 (PD-L1) expression can
assist in predicting whether a patient will respond to anti-PD-L1 therapy. In this study, we …

Expression of programmed cell death ligand 1 in non–small cell lung cancer: comparison between cytologic smears, core biopsies, and whole sections using the …

E Munari, G Zamboni, G Sighele… - Cancer …, 2019 - Wiley Online Library
Background Evaluation of programmed cell death ligand 1 (PD‐L1) expression can be
made on both resection specimens and diagnostic biopsies; however, more than 30% of …

Programmed cell death ligand 1-expressing circulating tumor cells: a new prognostic biomarker in non-small cell lung cancer

L Sinoquet, W Jacot, L Gauthier, S Pouderoux… - Clinical …, 2021 - academic.oup.com
Background In non-small cell lung cancer (NSCLC), analysis of programmed cell death
ligand 1 (PD-L1) expression in circulating tumor cells (CTCs) is a potential alternative to …

[HTML][HTML] Programmed Death Ligand-1 Testing in Adenocarcinoma Lung: A Comparative Study of Cell Block versus Biopsy

S Shukla, RK Pandey, V Gupta, N Husain… - Journal of …, 2023 - journals.lww.com
Background: Immunotherapy currently stands as a novel treatment option, specifically in
cases of advanced non-small cell lung carcinoma (NSCLC). Expression of programmed …

The expression of PD-L1 protein as a prognostic factor in lung squamous cell carcinoma

K Takada, T Okamoto, G Toyokawa, Y Kozuma… - Lung cancer, 2017 - Elsevier
Background Programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1)
pathway-targeted immunotherapy has become the standard option of care in the …

Usefulness of [18F]fluorodeoxyglucose PET/CT for evaluating the PD-L1 status in nasopharyngeal carcinoma

L Zhao, Y Zhuang, K Fu, P Chen, Y Wang… - European journal of …, 2020 - Springer
Purpose To explore the relationship between [18 F] fluorodeoxyglucose (18 F-FDG uptake)
and PD-L1 expression and determine the usefulness of 18 F-FDG PET/CT for evaluating the …

Association between PD-L1 expression and metabolic activity on 18F-FDG PET/CT in patients with small-sized lung cancer

K Takada, G Toyokawa, T Tagawa, K Kohashi… - Anticancer …, 2017 - ar.iiarjournals.org
Aim: We evaluated the metabolic characteristics of small-sized lung cancer using 18F-
fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG …

[HTML][HTML] Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer

J Sheng, W Fang, J Yu, N Chen, J Zhan, Y Ma… - Scientific reports, 2016 - nature.com
The effects of treatments to programmed death ligand-1 (PD-L1) expression is unknown.
The aim of this study was to investigate the impact of neoadjuvant chemotherapy (NACT) on …

Consistency Analysis of Programmed Death Ligand 1 Expression in Non–Small Cell Lung Cancer Between Pleural Effusion and Matched Primary Lung Cancer …

Z Sun, X Xiao, S Liang, H Ma, Y Sun, L Zhao… - Laboratory …, 2024 - Elsevier
In clinical practice, programmed death ligand 1 (PD-L1) detection is prone to nonspecific
staining due to the complex cellular composition of pleural effusion smears. In this study …

[HTML][HTML] Programmed death-ligand 1 copy number loss in NSCLC associates with reduced programmed death-ligand 1 tumor staining and a cold immunophenotype

S Aujla, C Aloe, A Vannitamby, S Hendry… - Journal of Thoracic …, 2022 - Elsevier
Introduction Programmed death-ligand 1 (PD-L1) copy number gains may be predictive of
clinical response to immunotherapy in NSCLC. This study investigated PD-L1 copy number …