HuD is a human neuronal specific RNA-binding protein. In this study we have purified HuD
and examined its RNA binding properties in detail. HuD binds to mRNAs that contain an AU …

An important paradigm for post‐transcriptional regulation is the control of cytoplasmic mRNA
stability mediated by AU‐rich elements (AREs) in the 3′ untranslated region of transcripts …

AU-rich sequence motifs (specifically sequences containing reiterations of AUUUA) are
found in the 3'untranslated region of mammalian mRNAs encoding cytokines, adhesion …

Approximately 3 000 genes are regulated in a time‐, tissue‐, and stimulus‐dependent
manner by degradation or stabilization of their mRNAs. The process is mediated by …

AREsite is an online resource for the detailed investigation of AU-rich elements (ARE) in
vertebrate mRNA 3′-untranslated regions (UTRs). AREs are one of the most prominent cis …

Expression of many proto‐oncogenes, cytokines and lymphokines is regulated by targeting
their messenger RNAs for rapid degradation. Essential signals for this control are AU‐rich …

The RNA-binding protein, HuR, is involved in the stabilization of AU-rich element-containing
mRNAs with products that are involved in cell-cycle progression, cell differentiation and …

An important mechanism of posttranscriptional gene regulation in mammalian cells is the
rapid degradation of messenger RNAs (mRNAs) signaled by AU-rich elements (AREs) in …

TIAR and HuR are mRNA-binding proteins that play important roles in the regulation of
translation. They both possess three RNA recognition motifs (RRMs) and bind to AU-rich …

Many short-lived mRNAs, including those encoding lymphokines, cytokines, and proto-
oncogenes, contain an AU-rich sequence in their 3'-untranslated regions. These AU …