Cardiovascular disease is a major cause of mortality and morbidity worldwide. Early growth
response-1 (Egr-1) plays a critical regulatory role in a range of experimental models of …

Significance: Cardiovascular diseases are seen to be a primary cause of death, and their
prevalence has significantly increased across the globe in the past few years. Several …

Coronary heart disease is the leading cause of mortality worldwide, affecting millions of men
and women every year. Elucidation of key signaling factors and their pathways are critical for …

The immediate-early gene product and zinc finger transcription factor early growth response
(Egr)-1 plays a key master regulatory role in multiple cardiovascular pathological processes …

Early growth response‐1 (Egr‐1) is a master regulator and transcriptional sensor in vascular
dysfunction and disease. This article reviews recent developments in our understanding of …

Early growth response-1 one gene (Egr-1), one of the immediate early response genes,
plays an important role in the adaptive response of the myocardium to hypertrophic stimuli …

Hyperactivation of proliferative and growth promoting pathways underlies the progression of
vessel remodeling, leading to vascular dysfunction. An upregulation of early growth …

Aim To investigate the association between the expression of early growth response 3
(Egr3), the level of interleukin-6 (IL-6) and interleukin-1ß (IL-1ß) as well as prognosis in …

Early growth response factor 1: a pleiotropic mediator of inducible gene expression Page 1
Abstract The zinc-finger transcription factor, early growth response factor-1 (Egr-1) is an …

Early growth response-1 (Egr-1) regulates expression of proinflammatory and procoagulant
genes in acute cell stress. Experimental evidence suggested that Egr-1 transcripts were …