The potential role of MUC16 (CA125) biomarker in lung cancer: a magic biomarker but with adversity
Lung cancer is the second most commonly diagnosed cancer in the world. In terms of the
diagnosis of lung cancer, combination carcinoembryonic antigen (CEA) and cancer antigen …
diagnosis of lung cancer, combination carcinoembryonic antigen (CEA) and cancer antigen …
MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress
M Felder, A Kapur, J Gonzalez-Bosquet, S Horibata… - Molecular cancer, 2014 - Springer
Over three decades have passed since the first report on the expression of CA125 by
ovarian tumors. Since that time our understanding of ovarian cancer biology has changed …
ovarian tumors. Since that time our understanding of ovarian cancer biology has changed …
Understanding the unique attributes of MUC16 (CA125): potential implications in targeted therapy
CA125, the most widely used ovarian cancer biomarker, was first identified approximately 35
years ago in an antibody screen against ovarian cancer antigen. Two decades later, it was …
years ago in an antibody screen against ovarian cancer antigen. Two decades later, it was …
MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse
Y Wang, DJ Cheon, Z Lu, SL Cunningham, CM Chen… - Differentiation, 2008 - Elsevier
Cancer antigen 125 (CA125) is an antigen that is elevated in the serum of women with
ovarian carcinoma, but can also be detected in serum from healthy women. CA125 is …
ovarian carcinoma, but can also be detected in serum from healthy women. CA125 is …
The evolving role of MUC16 (CA125) in the transformation of ovarian cells and the progression of neoplasia
P Giamougiannis, PL Martin-Hirsch, FL Martin - Carcinogenesis, 2021 - academic.oup.com
MUC16 (the cancer antigen CA125) is the most commonly used serum biomarker in
epithelial ovarian cancer, with increasing levels reflecting disease progression. It is a …
epithelial ovarian cancer, with increasing levels reflecting disease progression. It is a …
The role of CA 125 as tumor marker: biochemical and clinical aspects
CA 125 also known as mucin 16 or MUC16 is a large membrane glycoprotein belonging to
the wide mucin family, encoded by the homonymous MUC16 gene. Following its discovery …
the wide mucin family, encoded by the homonymous MUC16 gene. Following its discovery …
Expression of the carboxy-terminal portion of MUC16/CA125 induces transformation and tumor invasion
The CA125 antigen is found in the serum of many patients with serous ovarian cancer and
has been widely used as a disease marker. CA125 has been shown to be an independent …
has been widely used as a disease marker. CA125 has been shown to be an independent …
[HTML][HTML] CA125 (MUC16) gene silencing suppresses growth properties of ovarian and breast cancer cells
S Reinartz, S Failer, T Schuell, U Wagner - European Journal of Cancer, 2012 - Elsevier
The tumour-associated antigen CA125 (mucin 16, MUC16) is commonly expressed in
ovarian cancer, and can also be detected in other tumour of epithelial origin, but its …
ovarian cancer, and can also be detected in other tumour of epithelial origin, but its …
MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells
MUC16/CA125 is a tumor marker currently used in clinics for the follow-up of patients with
ovarian cancer. However, MUC16 expression is not entirely restricted to ovarian …
ovarian cancer. However, MUC16 expression is not entirely restricted to ovarian …
MUC16 facilitates cervical cancer progression via JAK2/STAT3 phosphorylation-mediated cyclooxygenase-2 expression
H Shen, M Guo, L Wang, X Cui - Genes & genomics, 2020 - Springer
Abstract Objectives MUC16 (mucin 16, also known as CA-125, cancer antigen 125,
carcinoma antigen 125, or carbohydrate antigen 125) has been predicted as tumor …
carcinoma antigen 125, or carbohydrate antigen 125) has been predicted as tumor …