B cells and autoantibodies in the pathogenesis of multiple sclerosis and related inflammatory demyelinating diseases

KA McLaughlin, KW Wucherpfennig - Advances in immunology, 2008 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …

Role of B cells in pathogenesis of multiple sclerosis

B Nikbin, MM Bonab, F Khosravi, F Talebian - International review of …, 2007 - Elsevier
Despite the current limited understanding of the etiology of multiple sclerosis (MS), genetic
susceptibility and environmental influences are known driving factors. MS is considered a T …

The role of B cells in multiple sclerosis: rationale for B-cell-targeted therapies

MK Racke - Current opinion in neurology, 2008 - journals.lww.com
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
with no clear etiology. Until recently, most studies have emphasized the role of T cells in the …

Role of B cells and antibodies in multiple sclerosis

P Wanleenuwat, P Iwanowski - Multiple sclerosis and related disorders, 2019 - Elsevier
Multiple sclerosis (MS) is a chronically progressive auto-immune mediated inflammatory
demyelinating disease of the central nervous system (CNS) which manifests as disturbances …

The role of B cells in the immunopathogenesis of multiple sclerosis

T Gharibi, Z Babaloo, A Hosseini, F Marofi… - …, 2020 - Wiley Online Library
There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis
(MS). The success of B‐cell targeting therapies in MS highlighted the role of B cells …

Cooperation of B cells and T cells in the pathogenesis of multiple sclerosis

MS Weber, B Hemmer - Molecular Basis of Multiple Sclerosis: The Immune …, 2010 - Springer
B cells and T cells are two major players in the pathogenesis of multiple sclerosis (MS) and
cooperate at various check points. B cells, besides serving as a source for antibody …

B cells in multiple sclerosis

H Wekerle - Autoimmunity, 2017 - Taylor & Francis
B lymphocytes have essential roles in the autoimmune pathogenesis of multiple sclerosis
(MS). They regulate the autoimmune response and participate in the development of the …

B cells in multiple sclerosis: connecting the dots

HC von Büdingen, A Bar-Or, SS Zamvil - Current opinion in immunology, 2011 - Elsevier
Over the past two decades B cells have increasingly moved into the spotlight in multiple
sclerosis (MS) research. This interest was fuelled by growing understanding and acceptance …

The Charcot Lecture| beating MS: a story of B cells, with twists and turns

SL Hauser - Multiple Sclerosis Journal, 2015 - journals.sagepub.com
Autoimmune B cells play a major role in mediating tissue damage in multiple sclerosis (MS).
In MS, B cells are believed to cross the blood-brain barrier and undergo stimulation, antigen …

[HTML][HTML] B cells and autoantibodies in multiple sclerosis

AK Pröbstel, NSR Sanderson, T Derfuss - International journal of …, 2015 - mdpi.com
While over the past decades T cells have been considered key players in the pathogenesis
of multiple sclerosis (MS), it has only recently become evident that B cells have a major …