Novel antiplatelet agents in cardiovascular disease

M Tscharre, AD Michelson… - Journal of …, 2020 - journals.sagepub.com
Antiplatelet therapy reduces atherothrombotic risk and has therefore become a cornerstone
in the treatment of cardiovascular disease. Aspirin, adenosine diphosphate P2Y12 receptor …

Current concepts and novel targets for antiplatelet therapy

M Gawaz, T Geisler, O Borst - Nature Reviews Cardiology, 2023 - nature.com
Platelets have a crucial role in haemostasis and atherothrombosis. Pharmacological control
of platelet hyper-reactivity has become a cornerstone in the prevention of thrombo …

[HTML][HTML] Novel aspects of antiplatelet therapy in cardiovascular disease

T Gremmel, AD Michelson, AL Frelinger III… - Research and practice in …, 2018 - Elsevier
Antiplatelet therapy is a cornerstone in the secondary prophylaxis of adverse cardiovascular
events such as myocardial infarction and stroke. The cyclooxygenase inhibitor aspirin …

New antithrombotic drugs

PL Gross, JI Weitz - Clinical Pharmacology & Therapeutics, 2009 - Wiley Online Library
Thrombosis, both venous and arterial, is a major cause of morbidity and mortality worldwide.
Consequently, there is an ongoing search for new antithrombotic drugs, particularly novel …

Antiplatelet strategies: past, present, and future

L Stanger, A Yamaguchi, M Holinstat - Journal of Thrombosis and …, 2023 - Elsevier
Antiplatelet therapy plays a critical role in the prevention and treatment of major
cardiovascular diseases triggered by thrombosis. Since the 1900s, significant progress in …

Novel antiplatelet agents: the current state and what is coming down the pike

F Franchi, F Rollini, Y Park, DJ Angiolillo - Progress in Cardiovascular …, 2015 - Elsevier
Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary
syndrome (ACS) or undergoing percutaneous coronary intervention (PCI). Despite the use …

Antiplatelet therapy

AH Gershlick - Hospital Medicine, 2000 - magonlinelibrary.com
Antiplatelet therapy Page 1 Hospital Medicine, January 2000, Vol 61, No 1 15 Platelet-initiated
thrombus plays a cen- tral role in the pathogenesis of coronary artery disease, especially in the …

Novel anti-platelet agents: focus on thrombin receptor antagonists

F de Souza Brito, P Tricoci - Journal of cardiovascular translational …, 2013 - Springer
Platelets are the key in the pathogenesis of atherothrombotic disease such as acute
coronary syndromes, stroke, and peripheral arterial disease. Current anti-platelet treatments …

Antithrombotic drugs—pharmacology and perspectives

T Li, D Yuan, J Yuan - Coronary artery disease: Therapeutics and drug …, 2020 - Springer
Thrombosis, the localized clotting of blood that affects arterial or venous circulation, is one of
the leading causes of death worldwide. Arterial thrombosis is commonly initiated by vascular …

New perspectives in antiplatelet therapy

A Tello-Montoliu, E Jover, J Rivera… - Current medicinal …, 2012 - ingentaconnect.com
Platelet activation is a complex mechanism of response to vascular injury and
atherothrombotic disease, leading to thrombus formation. A wide variety of surface receptors …