Characterization of serum cytokine profile in predominantly colonic inflammatory bowel disease to delineate ulcerative and Crohn's colitides

OY Korolkova, JN Myers, ST Pellom… - Clinical Medicine …, 2015 - journals.sagepub.com
Background As accessible diagnostic approaches fail to differentiate between ulcerative
colitis (UC) and Crohn's colitis (CC) in one-third of patients with predominantly colonic …

Role of serum cytokine profile in ulcerative colitis assessment

ML Rodríguez-Perlvárez… - Inflammatory bowel …, 2012 - academic.oup.com
Background Several cytokines are overexpressed in the colonic mucosa of patients with
ulcerative colitis (UC). The measurement of these parameters in plasma could be useful in …

Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn's disease

A Stallmach, T Giese, C Schmidt, B Ludwig… - International journal of …, 2004 - Springer
Background and aims Immunoregulatory properties of cytokines may contribute to
pathological immune reactions in inflammatory bowel disease. There is an urgent need for a …

Quantitive cytokine mRNA expression profiles in the colonic mucosa of patients with steroid naive ulcerative colitis during active and quiescent disease

R Matsuda, T Koide, C Tokoro… - Inflammatory bowel …, 2009 - academic.oup.com
Background Cytokines have validated roles in the immunopathogenesis of inflammatory
bowel disease (IBD). This study was to investigate the expressions of tumor necrosis factor …

Serum cytokine, chemokine, and growth factor profiles and their modulation in inflammatory bowel disease

ML Martinez-Fierro, I Garza-Veloz, MR Rocha-Pizaña… - Medicine, 2019 - journals.lww.com
Ulcerative colitis (UC) and Crohn disease (CD) are the most common forms of inflammatory
bowel disease (IBD). Because these subtypes of IBD are characterized by periods of activity …

Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease

GP Christophi, R Rong, PG Holtzapple… - Inflammatory bowel …, 2012 - academic.oup.com
Background Cytokine signaling pathways play a central role in the pathogenesis of
inflammatory bowel disease (IBD). Ulcerative colitis (UC) and Crohn's disease (CD) have …

[HTML][HTML] Laboratory markers in ulcerative colitis: Current insights and future advances

M Cioffi, A De Rosa, R Serao, I Picone… - World journal of …, 2015 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) and Crohn's disease (CD) are the major forms of inflammatory bowel
diseases (IBD) in man. Despite some common features, these forms can be distinguished by …

Monocytosis and a low lymphocyte to monocyte ratio are effective biomarkers of ulcerative colitis disease activity

CE Cherfane, L Gessel, D Cirillo… - Inflammatory bowel …, 2015 - academic.oup.com
Background Current biomarkers in ulcerative colitis (UC) are limited by their performance,
cost, and limited availability in daily practice. This study examined alterations in the …

Blood-based biomarkers used to predict disease activity in Crohn's disease and ulcerative colitis

R Burakoff, V Pabby, L Onyewadume… - Inflammatory bowel …, 2015 - academic.oup.com
Background Identifying specific genes that are differentially expressed during inflammatory
bowel disease flares may help stratify disease activity. The aim of this study was to identify …

Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis

A Zahn, T Giese, M Karner, A Braun, U Hinz… - BMC …, 2009 - Springer
Background A definition of disease activity in ulcerative colitis (UC) is difficult. The clinical
activity index (CAI) is only an indirect assessment tool of bowel inflammation and the …