Mimicking Parkinson's disease in a dish: merits and pitfalls of the most commonly used dopaminergic in vitro models
FM Lopes, IJ Bristot, LL Da Motta, RB Parsons… - NeuroMolecular …, 2017 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disorder and has
both unknown etiology and non-curative therapeutic options. Patients begin to present the …
both unknown etiology and non-curative therapeutic options. Patients begin to present the …
[HTML][HTML] Comprehensive perspectives on experimental models for Parkinson's disease
Parkinson's disease (PD) ranks second among the most common neurodegenerative
diseases, characterized by progressive and selective loss of dopaminergic neurons. Various …
diseases, characterized by progressive and selective loss of dopaminergic neurons. Various …
[HTML][HTML] Human brain-based models provide a powerful tool for the advancement of Parkinson's disease research and therapeutic development
SF McComish, AN MacMahon Copas… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease and
affects approximately 2–3% of the population over the age of 65. PD is characterised by the …
affects approximately 2–3% of the population over the age of 65. PD is characterised by the …
Animal models for preclinical Parkinson's research: an update and critical appraisal
MA Cenci, A Björklund - Progress in brain research, 2020 - Elsevier
Animal models of Parkinson's disease (PD) are essential to investigate pathogenic
pathways at the whole-organism level. Moreover, they are necessary for a preclinical …
pathways at the whole-organism level. Moreover, they are necessary for a preclinical …
[HTML][HTML] Animal models of Parkinson's disease: a gateway to therapeutics?
W Le, P Sayana, J Jankovic - Neurotherapeutics, 2014 - Elsevier
Parkinson's disease (PD) is a progressive, neurodegenerative disorder of unknown etiology,
although a complex interaction between environmental and genetic factors has been …
although a complex interaction between environmental and genetic factors has been …
[HTML][HTML] Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions
A Dovonou, C Bolduc, V Soto Linan, C Gora… - Translational …, 2023 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
Classic and evolving animal models in Parkinson's disease
Parkinson's disease (PD) is a progressive neurodegenerative disease with motor and non-
motor symptoms. PD is characterized by the degeneration of dopaminergic neurons in the …
motor symptoms. PD is characterized by the degeneration of dopaminergic neurons in the …
Animal models of Parkinson's disease: An updated overview
P Gubellini, P Kachidian - Revue neurologique, 2015 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder whose etiology,
besides a minority of genetic cases, is still largely unknown. Animal models have contributed …
besides a minority of genetic cases, is still largely unknown. Animal models have contributed …
[HTML][HTML] Animal Models of Parkinson's Disease: New models provide greater translational and predictive value
KM Gamber - Biotechniques, 2016 - Taylor & Francis
Parkinson's disease (PD) is a progressive neurodegenerative condition that results in
movement and cognitive disorders. PD arises from the degeneration of dopamine (DA) …
movement and cognitive disorders. PD arises from the degeneration of dopamine (DA) …
[HTML][HTML] Enhanced differentiation of human dopaminergic neuronal cell model for preclinical translational research in Parkinson's disease
Human-derived neuronal cell lines are progressively being utilized in understanding
neurobiology and preclinical translational research as they are biologically more relevant …
neurobiology and preclinical translational research as they are biologically more relevant …