Hyperpolarized 13C MRI: State of the Art and Future Directions
Hyperpolarized (HP) carbon 13 (13C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …
[HTML][HTML] Hyperpolarized 13C MRI: path to clinical translation in oncology
This white paper discusses prospects for advancing hyperpolarization technology to better
understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13 C …
understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13 C …
Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients
Purpose To develop and translate a metabolite‐specific imaging sequence using a
symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C) …
symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C) …
Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies
Hyperpolarized 13C MR spectroscopic imaging can detect not only the uptake of the pre‐
polarized molecule but also its metabolic products in vivo, thus providing a powerful new …
polarized molecule but also its metabolic products in vivo, thus providing a powerful new …
In Vivo Carbon-13 Dynamic MRS and MRSI of Normal and Fasted Rat Liver with Hyperpolarized 13C-Pyruvate
Background The use of in vivo 13 C nuclear magnetic resonance spectroscopy in probing
metabolic pathways to study normal metabolism and characterize disease physiology has …
metabolic pathways to study normal metabolism and characterize disease physiology has …
Multiband excitation pulses for hyperpolarized 13C dynamic chemical-shift imaging
Hyperpolarized 13C offers high signal-to-noise ratios for imaging metabolic activity in vivo,
but care must be taken when designing pulse sequences because the magnetization cannot …
but care must be taken when designing pulse sequences because the magnetization cannot …
Hyperpolarized C‐13 spectroscopic imaging of the TRAMP mouse at 3T—initial experience
AP Chen, MJ Albers, CH Cunningham… - … in Medicine: An …, 2007 - Wiley Online Library
The transgenic adenocarcinoma of mouse prostate (TRAMP) mouse is a well‐studied
murine model of prostate cancer with histopathology and disease progression that mimic the …
murine model of prostate cancer with histopathology and disease progression that mimic the …
Development of methods and feasibility of using hyperpolarized carbon‐13 imaging data for evaluating brain metabolism in patient studies
I Park, PEZ Larson, JW Gordon… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Hyperpolarized carbon‐13 (13C) metabolic imaging is a noninvasive imaging
modality for evaluating real‐time metabolism. The purpose of this study was to develop and …
modality for evaluating real‐time metabolism. The purpose of this study was to develop and …
Hyperpolarized 13C MRI: A novel approach for probing cerebral metabolism in health and neurological disease
Cerebral metabolism is tightly regulated and fundamental for healthy neurological function.
There is increasing evidence that alterations in this metabolism may be a precursor and …
There is increasing evidence that alterations in this metabolism may be a precursor and …
Imaging considerations for in vivo 13C metabolic mapping using hyperpolarized 13C‐pyruvate
One of the challenges of optimizing signal‐to‐noise ratio (SNR) and image quality in 13C
metabolic imaging using hyperpolarized 13C‐pyruvate is associated with the different MR …
metabolic imaging using hyperpolarized 13C‐pyruvate is associated with the different MR …