Field stimulation (10 Hz for 10 s, 0.5 ms pulse width, 60 V) of the guinea-pig isolated main
bronchi (atropine plus indomethacin in the bath) produced reproducible contractions which …

Vagal nerve stimulation (1 Hz for 1 min), capsaicin (10‐8 M and 10‐6 M), resiniferatoxin (3×
10‐10 M) and nicotine (10‐4 M) evoked a non‐cholinergic bronchoconstriction in the …

Field stimulation of the isolated main bronchi of the guinea-pig results in a rapid contraction
followed by a sustained contractile response. Tetrodotoxin abolished these effects. The first …

We investigated the action of capsazepine, an antagonist of the actions of capsaicin on
sensory neurones, on the contractile responses evoked by capsaicin or by electrical field …

Electrical stimulation of the right vagus nerve causes a biphasic contraction of the guinea pig
isolated right bronchus. The" first-phase" is blocked by hexamethonium or atropine and the" …

Sensory mechanisms play an important role in the vagal regulation of tracheobronchial
smooth muscle tone. Thus, activation of various types of “irritant receptors” in the respiratory …

Contraction of the isolated tracheal strip to capsaicin was prevented by chronic denervation
of the tissue. Tetrodotoxin, hyoscine and hexamethonium caused no inhibition of the …

We have examined the effects of low pH and the selectivity of the capsaicin antagonist
capsazepine on single sensory fibres innervating the guinea-pig trachea in vitro, and on the …

In order to reveal the role of axon reflexes and sensory receptors in sensory neuropeptide
release in response to capsaicin, liberation of substance P, calcitonin gene-related peptide …

We have investigated the ability of Ruthenium Red, an inorganic dye with calcium entry
blocking properties, to interfere with the 'efferent'function of capsaicin-sensitive sensory …