Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP
M Nagai, K Usuku, W Matsumoto, D Kodama… - Journal of …, 1998 - Taylor & Francis
In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we
measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a …
measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a …
HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years
T Matsuzaki, M Nakagawa, M Nagai, K Usuku… - Journal of …, 2001 - Springer
To clarify clinical and laboratory findings that may be related to the pathomechanism of
HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), we analyzed these …
HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), we analyzed these …
HTLV-1 proviral load in peripheral blood mononuclear cells quantified in 100 HAM/TSP patients: a marker of disease progression
S Olindo, A Lézin, P Cabre, H Merle, M Saint-Vil… - Journal of the …, 2005 - Elsevier
A high proviral load of human T cell lymphotropic virus type 1 (HTLV-1) in peripheral blood
mononuclear cells (PBMCs) has been reported in patients with HTLV-1-associated …
mononuclear cells (PBMCs) has been reported in patients with HTLV-1-associated …
Fluctuation of HTLV-I proviral DNA in peripheral blood mononuclear cells of HTLV-I-associated myelopathy
R Kubota, T Fujiyoshi, S Izumo, S Yashiki… - Journal of …, 1993 - Elsevier
To assess the immunopathological significance of the increased replication of human T-cell
leukemia virus type I (HTLV-I) in HTLV-I-associated myelopathy/tropical spastic paraparesis …
leukemia virus type I (HTLV-I) in HTLV-I-associated myelopathy/tropical spastic paraparesis …
HTLV-I specific IFN-γ+ CD8+ lymphocytes correlate with the proviral load in peripheral blood of infected individuals
R Kubota, T Kawanishi, H Matsubara, A Manns… - Journal of …, 2000 - Elsevier
Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is an inflammatory neurological disease caused by HTLV-I infection …
paraparesis (HAM/TSP) is an inflammatory neurological disease caused by HTLV-I infection …
Human T cell lymphotropic virus type 1 (HTLV‐1) proviral load of HTLV‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients according to new …
MFR Grassi, VN Olavarria… - Journal of medical …, 2011 - Wiley Online Library
A high human T‐cell lymphotropic virus type 1 (HTLV‐1) proviral load is described in HTLV‐
1‐associated diseases, especially HAM/TSP. However, the cut‐off value to define high …
1‐associated diseases, especially HAM/TSP. However, the cut‐off value to define high …
[HTML][HTML] In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy …
M Saito, T Matsuzaki, Y Satou, J Yasunaga, K Saito… - Retrovirology, 2009 - Springer
Background Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper
factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to …
factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to …
Increased HTLV‐I proviral load and preferential expansion of HTLV‐I tax‐specific CD8+ T cells in cerebrospinal fluid from patients with HAM/TSP
M Nagai, Y Yamano, MB Brennan, CA Mora… - Annals of …, 2001 - Wiley Online Library
To date, high human T‐cell lymphotropic virus type I proviral load in patients with human T‐
cell lymphotropic virus type I‐associated myelopathy/tropical spastic paraparesis has been …
cell lymphotropic virus type I‐associated myelopathy/tropical spastic paraparesis has been …
HTLV-I proviral DNA amount correlates with infiltrating CD4+ lymphocytes in the spinal cord from patients with HTLV-I-associated myelopathy
R Kubota, F Umehara, S Izumo, S Ijichi… - Journal of …, 1994 - Elsevier
A quantitative method utilizing polymerase chain reaction was employed to evaluate the
amount of human T-cell leukemia virus type I (HTLV-I) proviral DNA in the affected spinal …
amount of human T-cell leukemia virus type I (HTLV-I) proviral DNA in the affected spinal …
HTLV-I-associated myelopathy: analysis of 213 patients based on clinical features and laboratory findings
M Nakagawa, S Izumo, S Ijichi, H Kubota… - Journal of …, 1995 - Taylor & Francis
We studied the clinical features and laboratory findings in 213 patients with HTLV-I-
associated myelopathy/tropical spastic paraparesis as diagnosed in Kagoshima University …
associated myelopathy/tropical spastic paraparesis as diagnosed in Kagoshima University …