A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss
A Parle-McDermott, F Pangilinan… - Molecular human …, 2005 - academic.oup.com
Low maternal folate or vitamin B12 status has been implicated in numerous pregnancy
complications including spontaneous abortion. The primary aim of this study was to test a …
complications including spontaneous abortion. The primary aim of this study was to test a …
Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy
M Enciso, J Sarasa, L Xanthopoulou, S Bristow… - Human genetics, 2016 - Springer
MTHFR is an important enzyme in the metabolism of folic acid and is crucial for reproductive
function. Variation in the sequence of MTHFR has been implicated in subfertility, but …
function. Variation in the sequence of MTHFR has been implicated in subfertility, but …
[HTML][HTML] Methylenetetrahydrofolate reductase polymorphisms and pregnancy outcome
M Turgal, F Gumruk, E Karaagaoglu… - Geburtshilfe und …, 2018 - thieme-connect.com
Introduction Aim of the study was to evaluate the effect of methylenetetrahydrofolate
reductase (MTHFR) polymorphisms on pregnancy outcome. Materials and Methods A total …
reductase (MTHFR) polymorphisms on pregnancy outcome. Materials and Methods A total …
[HTML][HTML] Methylenetetrahydrofolate reductase and transcobalamin genetic polymorphisms in human spontaneous abortion: biological and clinical implications
H Zetterberg - Reproductive Biology and Endocrinology, 2004 - Springer
The pathogenesis of human spontaneous abortion involves a complex interaction of several
genetic and environmental factors. The firm association between increased homocysteine …
genetic and environmental factors. The firm association between increased homocysteine …
Methylenetetrahydrofolate reductase C677T polymorphism and pregnancy complications
F Stonek, E Hafner, K Philipp, LA Hefler… - Obstetrics & …, 2007 - journals.lww.com
OBJECTIVE: To investigate the frequency of the methylenetetrahydrofolate reductase
(MTHFR) C677T polymorphism in women with intrauterine fetal death, preeclampsia …
(MTHFR) C677T polymorphism in women with intrauterine fetal death, preeclampsia …
Gene–gene interaction between fetal MTHFR 677C> T and transcobalamin 776C> G polymorphisms in human spontaneous abortion
BACKGROUND: Genetic polymorphisms in the methylenetetrahydrofolate reductase
(MTHFR) and transcobalamin (TC) genes influence homocysteine metabolism which in turn …
(MTHFR) and transcobalamin (TC) genes influence homocysteine metabolism which in turn …
Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption
CV Ananth, MR Peltier, C De Marco… - American Journal of …, 2007 - Elsevier
OBJECTIVE: Heritable thrombophilias have been implicated as a potential cause of
abruption by vascular disruption at the uteroplacental interface. Polymorphisms of the …
abruption by vascular disruption at the uteroplacental interface. Polymorphisms of the …
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study
PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) is involved in the metabolism of
folate and homocysteine; a polymorphism in the MTHFR gene (677C→ T) has been …
folate and homocysteine; a polymorphism in the MTHFR gene (677C→ T) has been …
[HTML][HTML] Association of maternal and fetal MTHFR A1298C polymorphism with the risk of pregnancy loss: a study of an Indian population and a meta-analysis
OBJECTIVE: To study the genetic association between methylenetetrahydrofolate reductase
(MTHFR) A1298 polymorphism and recurrent pregnancy loss (RPL). DESIGN: Prospective …
(MTHFR) A1298 polymorphism and recurrent pregnancy loss (RPL). DESIGN: Prospective …
The C677T polymorphism of the methylenetetrahydrofolate reductase gene and idiopathic recurrent miscarriage
G Unfried, A Griesmacher, W Weismüller… - Obstetrics & …, 2002 - journals.lww.com
OBJECTIVE To investigate the association between the C677T polymorphism of the 5, 10-
methylenetetrahydrofolate reductase gene (MTHFR), serum homocysteine levels, and …
methylenetetrahydrofolate reductase gene (MTHFR), serum homocysteine levels, and …