Design and immunogenicity analysis of the combined vaccine against zoonotic hepatitis E and foot-and-mouth disease

Z Liu, N Behloul, S Baha, W Wei, R Shi, J Meng - Vaccine, 2019 - Elsevier
Aim Design and immunogenicity assessment of the combined vaccine candidate against
zoonotic hepatitis E virus (HEV) and foot-and-mouth disease virus (FMDV). Methods Using …

[HTML][HTML] Design and development of a chimeric vaccine candidate against zoonotic hepatitis E and foot-and-mouth disease

N Behloul, S Baha, Z Liu, W Wei, Y Zhu, Y Rao… - Microbial Cell …, 2020 - Springer
Background Zoonotic hepatitis E virus (HEV) infection emerged as a serious threat in the
industrialized countries. The aim of this study is exploring a new approach for the control of …

A novel multi-epitope peptide vaccine candidate targeting Hepatitis E virus: An in-silico approach

A Kumar, U Sahu, G Agnihotri, A Dixit, P Khare - bioRxiv, 2022 - biorxiv.org
HEV is a foodborne virus transmitted through the fecal-oral route that causes viral hepatitis
in humans worldwide. Ever since its discovery as a zoonotic agent, HEV was isolated from …

[HTML][HTML] Hepatitis E vaccines: a mini review

T Ahmad, H Haroon, K Ahmad, SM Shah… - … Research and Therapy, 2021 - bmrat.com
The hepatitis E virus (HEV) is an important public health concern and a significant cause of
enterically-transmitted viral hepatitis infections. HEV infection remains a serious threat to life …

Development of new hepatitis E vaccines

Y Cao, Z Bing, S Guan, Z Zhang… - Human Vaccines & …, 2018 - Taylor & Francis
Hepatitis E virus (HEV) infection is an emerging zoonotic disease posing a severe threat to
public health in the world, especially to pregnant women. Currently, no specific treatments …

Making the case for the development of a vaccination against hepatitis E virus

S Haffar, F Bazerbachi, JR Lake - Liver International, 2015 - Wiley Online Library
Hepatitis E virus (HEV) infection is a global problem that affects 20 million individuals, and
cause acute hepatitis in 3.5 million, with approximately 70 000 deaths worldwide per year …

[HTML][HTML] Vaccine development against zoonotic hepatitis E virus: open questions and remaining challenges

Y Nan, C Wu, Q Zhao, Y Sun, YJ Zhang… - Frontiers in …, 2018 - frontiersin.org
Hepatitis E virus (HEV) is a fecal-orally transmitted foodborne viral pathogen that causes
acute hepatitis in humans and is responsible for hepatitis E outbreaks worldwide. Since the …

A novel linear neutralizing epitope of hepatitis E virus

ZM Tang, M Tang, M Zhao, GP Wen, F Yang, W Cai… - Vaccine, 2015 - Elsevier
Hepatitis E virus (HEV) is a serious public health problem that causes acute hepatitis in
humans and is primarily transmitted through fecal and oral routes. The major anti-HEV …

[HTML][HTML] Multi-epitope vaccine design for hepatitis E virus based on protein ORF2 and ORF3

Q Lu, H Wu, J Meng, J Wang, J Wu, S Liu… - Frontiers in …, 2024 - frontiersin.org
Introduction Hepatitis E virus (HEV), with heightened virulence in immunocompromised
individuals and pregnant women, is a pervasive threat in developing countries. A globaly …

Design and production of a multiepitope construct derived from hepatitis E virus capsid protein

R Taherkhani, F Farshadpour… - Journal of Medical …, 2015 - Wiley Online Library
The aim of this study was to design a high density multiepitope protein, which can be a
promising multiepitope vaccine candidate against Hepatitis E virus (HEV). Initially …