Non-communicable diseases (NCDs) like cardiovascular disease, chronic respiratory
diseases, cancers, diabetes, and neuropsychiatric diseases cause significant global …

Helminth infections are highly prevalent in developing countries, especially in rural areas.
With gradual development, there is a transition from living conditions that are dominated by …

There is unequivocal evidence that parasites influence the immune activity of their hosts,
and many of the classical examples of this are drawn from assessment of helminth infections …

Exposure to commensal and pathogenic organisms strongly influences our immune system.
Exposure to helminths was frequent before humans constructed their current highly hygienic …

Successful endoparasites of mammals must outwit the sophisticated immune systems of
their hosts that have evolved to detect and destroy/eradicate them. Many species of helminth …

Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Immune-mediated diseases (eg inflammatory bowel disease, asthma, multiple sclerosis and
autoimmune diabetes) are increasing in prevalence and emerge as populations adopt …

The profile of global health today presents a striking reciprocal distribution between parasitic
diseases in many of the world's lower-income countries, and ever-increasing levels of …

Author Summary Current iterations of the hygiene hypothesis suggest an adaptive role for
helminth parasites in shaping the proper maturation of the immune system. However …

Helminthic infection has become rare in highly industrialized nations. Concurrent with the
decline in helminthic infection has been an increase in the prevalence of inflammatory …