Glycosphingolipids (GSLs) from Sphingomonas paucimobilis Increase the Efficacy of Liposome-Based Nanovaccine against Acinetobacter baumannii-Associated …

MA Khan, KS Allemailem, H Maswadeh, H Younus - Molecules, 2022 - mdpi.com
Due to the high propensity of drug resistance in Acinetobacter baumannii, the number of
currently available therapeutic drugs has become very limited. Thus, it becomes incredibly …

Safety and Prophylactic Efficacy of Liposome-Based Vaccine against the Drug-Resistant Acinetobacter baumannii in Mice

MA Khan, KS Allemailem, H Maswadeh, H Younus - Pharmaceutics, 2022 - mdpi.com
In recent years, the emergence of multidrug-resistant Acientobacter baumannii has greatly
threatened public health and depleted our currently available antibacterial armory. Due to …

[HTML][HTML] Liposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus

TC Rodrigues, DB Figueiredo, VM Gonçalves… - Journal of Controlled …, 2024 - Elsevier
Streptococcus pneumoniae is an important human pathogen. Currently used conjugate
vaccines are effective against invasive disease, but protection is restricted to serotypes …

Immunogenic Evaluation of MPEG-PCL & PLGA Nanoparticles Containing Klebsiella pneumoniae K2O1 Capsular Antigen in Pulmonary Infection Model of Mice

P Ghaderinia, R Shapouri… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Klebsiella pneumoniae can cause destructive changes to human lungs if aspirated. The
present study aimed to evaluate the immunogenicity of the carriers of Poly lactic-co-glycolic …

Evaluation of PLGA nanoparticles containing outer membrane proteins of Acinetobacter baumannii bacterium in stimulating the immune system in mice

A Gholizadeh, R Shapoury, P Pakzad… - Research in …, 2022 - journals.lww.com
Background and purpose: Acinetobacter baumannii (A. baumannii) is known as a pathogen
with antibiotic resistance, causing respiratory infections. PLGA has been approved for use in …

Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response …

X Pu, Y Wang, X Wang, X Sang, M Jiang… - Molecular …, 2024 - ACS Publications
Tuberculosis (TB) is a chronic disease caused by Mycobacterium tuberculosis (Mtb), which
shows a long treatment cycle often leads to drug resistance, making treatment more difficult …

Bovine serum albumin nanoparticle vaccine reduces lung pathology induced by live Pseudomonas aeruginosa infection in mice

NF Rodrigues, E van Tilburg Bernardes, RP Rocha… - Vaccine, 2013 - Elsevier
Pseudomonas aeruginosa is an important opportunistic human pathogen that causes
severe infections in immunocompromised patients and also in cystic fibrosis patients. The …

Protective potential of Conjugated P. aeruginosa LPS–PLGA nanoparticles in mice as a Nanovaccine

L Safari Zanjani, R Shapoury, M Dezfulian… - Iranian Journal of …, 2020 - iji.sums.ac.ir
Background: Pseudomonas aeruginosa has an important role in nosocomial infections.
Objective: To evaluate biological activity of the detoxified LPS (D-LPS) entrapped into Poly …

Single-dose of hybrid eukaryotic-prokaryotic nanovesicles to drive a rapid and controllable immune response against Klebsiella pneumoniae induced nosocomial …

L Jiang, L Ding, Q Long, X Liu, J Li, J Ma, Y Zheng… - Nano Today, 2024 - Elsevier
Klebsiella pneumoniae is the main pathogen of hospital-acquired infections causing acute
pneumonia, which is characterized by drug resistance, virulence and mortality, and for which …

Immunization With Mycobacterium tuberculosis Antigens Encapsulated in Phosphatidylserine Liposomes Improves Protection Afforded by BCG

GR Diogo, P Hart, A Copland, MY Kim… - Frontiers in …, 2019 - frontiersin.org
Liposomes have been long considered as a vaccine delivery system but this technology
remains to be fully utilized. Here, we describe a novel liposome-based subunit vaccine …