Intestinal ischemia-reperfusion (I/R) injury is a life-threatening vascular emergency and has
long been a disturbing problem for surgeons. Oxidative stress is considered a vital factor in …

Abstract Ginsenoside Rg1 (Rg1) is one of the major bioactive ingredients in Panax ginseng,
and it attenuates inflammation and apoptosis. The aims of our study were to explore the …

Background Intestinal ischemia-reperfusion injury occurs in acute intestinal obstruction,
intussusception, acute mesenteric artery embolism, and other diseases and can lead to local …

Pyroptosis is a form of programmed cell death initiated by inflammasomes and is critical for
immunity. SIRT1, a NAD+-dependent deacetylase, plays multiple roles in inflammatory …

Crohn's disease (CD) is a kind of refractory intestinal inflammatory diseases. Pyroptosis was
recently identified as a gasdermin-mediated proinflammatory cell death. However, it is …

We previously reported that Tangshen formula (TSF), a Chinese herbal medicine for diabetic
kidney disease (DKD) therapy, imparts renal protective effects. However, the underlying …

Ischemia-reperfusion (I/R) injury is a manifestation of tissue or organ damage that is
followed by ischemia and exacerbated by the return of blood flow to a previously damaged …

Pyroptosis, one kind of inflammatory regulated cell death, is involved in various inflammatory
diseases, including acute kidney injury (AKI). Besides Gasdermin D (GSDMD), GSDME is a …

Abstract Ischemia/reperfusion (I/R) injury is a life-threatening vascular emergency following
myocardial infarction. Our previous study showed cardioprotective effects of metformin …

We recently found that Sodium butyrate (NaB) possesses anti-inflammatory effects in
diabetic nephropathy (DN) mouse model and in high-glucose induced mouse glomerular …