BACKGROUND: Mesenchymal stem cells derived from adipose tissue have been
successfully used to promote sphincter-saving anal fistula healing. OBJECTIVE: The aim of …

BACKGROUND: In this study, we aimed to investigate the early results of the safety and
efficacy of adipose-derived stem cells (ADSCs) injection along with the repair of the internal …

Background: Autologous adipose-derived stem cells may represent a novel approach for the
management of complex fistula-in-ano. After successful phase I and II clinical trials, a phase …

Purpose Injection of adipose tissue-derived stem cells (ASCs) is a novel method for the
treatment of complex perianal fistulas. We aimed to evaluate the safety and efficacy of ASCs …

BACKGROUND: Anal fistula treatment aims to eradicate the fistula, preserve the sphincter,
prevent recurrence, and allow an early return to daily activities for the patient. Because of the …

PURPOSE: The feasibility and safety of stem cell-based therapy with expanded adipose-
derived stem cells (ASCs) has been investigated in a phase I clinical trial. The present study …

Purpose In patients with perianal fistulas, administration of adult stem cells (ASCs) derived
from liposuction samples has proved a promising technique in a preceding phase II trial. We …

The aim of this clinical trial (ID Number NCT01803347) was to determine the safety and
efficacy of autologous adipose-derived stem cells (ASCs) for treatment of cryptoglandular …

BACKGROUND: Treatment of cryptoglandular anal fistulas with injection of autologous or
allogenic adipose tissue–derived mesenchymal stem cells has shown promising results …

Risk of recurrence after surgical treatment of a recurrent fistula is up to 50%. It has be known
that more aggressive surgical treatment is associated with a high risk of anal sphincter …