The accidental overdose of local anesthetics may prove fatal. The commonly used amide
local anesthetics have varying adverse effects on the myocardium, and beyond a certain …

Cardiovascular collapse from accidental local anesthetic toxicity is a rare but catastrophic
complication of regional anesthesia. The long-acting amide local anesthetics bupivacaine …

Local anesthetic toxicity can have catastrophic outcome in an otherwise benign procedure.
Introduction of even a small amount of local anesthetic into the bloodstream can cause …

Background Local anesthetic systemic toxicity (LAST), including cardiovascular (CV) and
central nervous system (CNS) complications, is a rare but devastating complication of …

Lipid resuscitation for local anesthetic toxicity: is it rea... : Current Opinion in Anesthesiology
Lipid resuscitation for local anesthetic toxicity: is it really lifesaving? : Current Opinion in …

Systemic local anaesthetic toxicity is a rare but potentially fatal complication of regional
anaesthesia. This toxicity is due to inhibition of ionotropic and metabotropic cell signal …

Background Lipid emulsion infusion reverses cardiac toxicity of local anesthetics. The
predominant effect is likely creation of a" lipid sink." This in vitro study determined the extent …

Lipid emulsion has been shown to be an effective treatment for systemic toxicity induced by
local anesthetics, which is reflected in case reports. A systemic review and meta-analysis …

There is little question that the absolute, scientific “proof” of lipid emulsion's efficacy in
reversing local anesthetic-induced cardiac arrest is yet lacking. Such a proof would require …

Introduction The use of intravenous lipid emulsion (IVLE) has been proposed as a new
potential treatment for local anesthetic toxicity. Local anesthetics work through reversible …