Resveratrol reverses endothelial colony-forming cell dysfunction in adulthood in a rat model of intrauterine growth restriction

E Guillot, A Lemay, M Allouche, S Vitorino Silva… - International Journal of …, 2023 - mdpi.com
Individuals born after intrauterine growth restriction (IUGR) are at risk of developing
cardiovascular diseases (CVDs). Endothelial dysfunction plays a role in the pathogenesis of …

Intrauterine growth restriction-induced deleterious adaptations in endothelial progenitor cells: possible mechanism to impair endothelial function

V Oliveira, LV De Souza, T Fernandes… - … Origins of Health and …, 2017 - cambridge.org
Intrauterine growth restriction (IUGR) can induce deleterious changes in the modulatory
ability of the vascular endothelium, contributing to an increased risk of developing …

Endothelial colony-forming cells dysfunctions are associated with arterial hypertension in a rat model of intrauterine growth restriction

S Simoncini, H Coppola, A Rocca, I Bachmann… - International Journal of …, 2021 - mdpi.com
Infants born after intrauterine growth restriction (IUGR) are at risk of developing arterial
hypertension at adulthood. The endothelium plays a major role in the pathogenesis of …

Resveratrol protects late endothelial progenitor cells from TNF-α-induced inflammatory damage by upregulating Krüppel-like factor-2

H Chu, H Li, X Guan, H Yan… - Molecular …, 2018 - spandidos-publications.com
Cardiovascular risk factors can negatively influence late endothelial progenitor cell (EPCs)
number and functions, thus EPCs biology is a clinical implications for cardiovascular …

Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR‑γ/HO‑1 pathways

X Shen, M Wang, X Bi, J Zhang… - Molecular …, 2016 - spandidos-publications.com
Increasing evidence suggests endothelial progenitor cells (EPCs) improve
neovascularization and endothelium regeneration. Resveratrol (RSV) is a natural …

59 Endothelial colony forming cells (ECFC) are senescent and dysfunctional in COPD due to reduced sirtuin-1 levels

K Paschalaki, RD Starke, N Mercado, DO Haskard… - Heart, 2011 - heart.bmj.com
Introduction Cardiovascular disease (CVD) is a major cause of death in chronic obstructive
pulmonary disease (COPD). Numerous studies describe clinical evidence of endothelial …

Endothelial progenitor cell impairment mediated vasodilation dysfunction via diminishing nitric oxide production in postmenopausal females

WZ Wu, DJ Hu, ZY Wang… - Molecular Medicine …, 2019 - spandidos-publications.com
Vascular endothelial dysfunction is the major contributing factor to hypertension. Endothelial
progenitor cells (EPCs) are essential for endogenous vascular endothelial renovation. The …

Resveratrol alleviates Ang II-induced vascular smooth muscle cell senescence by upregulating E2F1/SOD2 axis

L Liu, X Yang, Y Liao, C Wang, Y Wang - Toxicology Research, 2022 - academic.oup.com
Background Vascular smooth muscle cells (VSMCs) senescence is a crucial factor relevant
to accelerate cardiovascular diseases. Resveratrol (RES) has been reported that could …

Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns

Q He, X Liu, Y Zhong, SS Xu, ZM Zhang… - Nutrition, Metabolism …, 2018 - Elsevier
Background and aims Intrauterine growth restriction (IUGR) is a major risk factor for perinatal
morbidity and mortality, leading to long-term adverse cardiovascular outcomes. The present …

Endothelial colony-forming cells derived from pregnancies complicated by intrauterine growth restriction are fewer and have reduced vasculogenic capacity

PI Sipos, SL Bourque, CA Hubel… - The Journal of …, 2013 - academic.oup.com
Context: Endothelial colony-forming cells (ECFCs) are the only putative endothelial
progenitor cells capable of vasculogenesis, and their dysfunction may represent a risk factor …