[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components

K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

[HTML][HTML] Ferroptosis and its multifaceted roles in cerebral stroke

Y Zhang, X Lu, B Tai, W Li, T Li - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Ferroptosis is a unique regulated cell death defined by the intracellular iron overload and
distinct biological features compared with other well-known programmed cell death …

Emerging role of ferroptosis in the pathogenesis of ischemic stroke: a new therapeutic target?

ZQ Bu, HY Yu, J Wang, X He, YR Cui, JC Feng… - ASN …, 2021 - journals.sagepub.com
Ischemic stroke is one of the main causes of high morbidity, mortality, and disability
worldwide; however, the treatment methods are limited and do not always achieve …

[HTML][HTML] Ferroptosis: a new strategy for traditional Chinese medicine treatment of stroke

Y Lou, M Ma, Y Jiang, H Xu, Z Gao, L Gao… - Biomedicine & …, 2022 - Elsevier
Stroke is a serious threat to human survival and health due to its high morbidity and
mortality. The pathological mechanism of stroke is complex and involves various regulated …

Pharmacological inhibition of ferroptosis as a therapeutic target for neurodegenerative diseases and strokes

Y Wang, S Wu, Q Li, H Sun, H Wang - Advanced Science, 2023 - Wiley Online Library
Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

[HTML][HTML] Ferroptosis—A Novel Mechanism With Multifaceted Actions on Stroke

XL Fang, SY Ding, XZ Du, JH Wang, XL Li - Frontiers in Neurology, 2022 - frontiersin.org
As a neurological disease with high morbidity, disability, and mortality, the pathological
mechanism underlying stroke involves complex processes such as neuroinflammation …

[HTML][HTML] Role and mechanism of ferroptosis in neurological diseases

M Ou, Y Jiang, Y Ji, Q Zhou, Z Du, H Zhu, Z Zhou - Molecular Metabolism, 2022 - Elsevier
Background Ferroptosis, as a new form of cell death, is different from other cell deaths such
as autophagy or senescence. Ferroptosis involves in the pathophysiological progress of …

New insights in ferroptosis: Potential therapeutic targets for the treatment of ischemic stroke

Z Wei, Y Xie, M Wei, H Zhao, K Ren, Q Feng… - Frontiers in …, 2022 - frontiersin.org
Stroke is a common disease in clinical practice, which seriously endangers people's
physical and mental health. The neurovascular unit (NVU) plays a key role in the occurrence …

Ferroptosis: An emerging therapeutic target in stroke

Y Liu, Y Fang, Z Zhang, Y Luo, A Zhang… - Journal of …, 2022 - Wiley Online Library
Stroke is a disastrous neurological disease with high morbidity and mortality. The
mechanism of the pathological process is extremely complicated and unclear. Although …

[HTML][HTML] Crosstalk between oxidative stress and ferroptosis/oxytosis in ischemic stroke: possible targets and molecular mechanisms

JX Ren, C Li, XL Yan, Y Qu, Y Yang… - Oxidative Medicine and …, 2021 - hindawi.com
Oxidative stress is a key cause of ischemic stroke and an initiator of neuronal dysfunction
and death, mainly through the overproduction of peroxides and the depletion of antioxidants …