Enzymatic oxidation or autooxidation of esterified polyunsaturated fatty acids (PUFA)
residues within phospholipids in cell membranes or circulating lipoprotein particles leads to …

Biologically active oxidized phospholipids can initiate and modulate many of the cellular
events attributed to inflammation leading to atherosclerosis. Produced by enzymatic or non …

Objectives: The purpose of this work was to determine the predictive value of oxidized
phospholipids (OxPLs) present on apolipoprotein B-100 particles (apoB) in carotid and …

Angiogenesis is a common feature observed in advanced atherosclerotic lesions. We
hypothesized that oxidized phospholipids (OxPLs), which accumulate in atherosclerotic …

Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

Long thought of as a bystander in pathophysiological processes, lipid molecules have
emerged as bioactive mediators of cellular activity. Oxidized phospholipids (OxPLs) …

Chronic inflammatory diseases including atherosclerosis are major causes of morbidity and
mortality worldwide. However, the factors, which trigger processes that determine the …

Over the past decade, there has been intense investigation in trying to understand the
pathological role that oxidized phospholipids play in cardiovascular disease. Phospholipids …

Aim Oxidized phospholipids (OxPL) are the major pathogenic component of oxidized low-
density lipoproteins (OxLDL). Endogenous anti-OxPL activity, defined as the ability to …

As chronic inflammatory processes are now understood to underpin the development of
atherosclerosis, and oxidative modification of lipids and lipoproteins has long been …